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南京医科大学学报(自然科学版) 第45卷第11期
·1662 · Journal of Nanjing Medical University(Natural Sciences) 2025年11月
·临床研究·
肺单孔胸腔镜术后高脂肪饮食对迟发性胸腔积液影响的倾向
性匹配研究
蒋 捷,刘 锋,钟 健,王 波,王 芹 *
南京医科大学附属脑科医院胸外科,江苏 南京 210029
[摘 要] 目的:探索肺单孔胸腔镜术后高脂肪饮食对迟发性胸腔积液的影响。方法:回顾性分析2021年12月—2023年6月
于南京医科大学附属脑科医院胸外科接受单孔胸腔镜肺手术的571例患者临床资料。按照术后是否高脂肪饮食将患者分为
高脂肪饮食组以及非高脂肪饮食组(对照组)。采用倾向性评分匹配研究方法,按照1∶1比例将两组患者进行匹配,比较匹配
后的两组患者术后迟发性胸腔积液以及其他术后并发症发生率。结果:匹配前高脂肪饮食组纳入患者166例,其中男45例,女
121例,年龄56.0(49.0,66.0)岁;对照组纳入患者405例,其中男164例,女241例,中位年龄57.0(48.0,67.0)岁。采用倾向性匹
配后两组各纳入130例,其中高脂肪饮食组术后迟发型胸腔积液发生率(OR=1.080,95%CI:1.013~1.152,P=0.019)、术后咳嗽
发生率(OR=1.203,95%CI:1.091~1.326,P=0.001)、术后胸闷发生率(OR=1.166,95%CI:1.038~1.311,P=0.010)均明显高于对照
组,差异均有统计学意义。结论:单孔胸腔镜肺术后高脂肪饮食可明显增加术后迟发型胸腔积液发生率。
[关键词] 单孔胸腔镜手术;胸腔积液;高脂肪饮食;倾向性评分匹配
[中图分类号] R561.3 [文献标志码] A [文章编号] 1007⁃4368(2025)11⁃1662⁃08
doi:10.7655/NYDXBNSN250229
A propensity score matched study on the impact of high ⁃ fat diet on delayed pleural
effusion after single⁃port video⁃assisted thoracoscopic lung surgery
*
JIANG Jie,LIU Feng,ZHONG Jian,WANG Bo,WANG Qin
Department of Thoracic Surgery,the Affiliated Brain Hospital of Nanjing Medical University,Nanjing,210029,China
[Abstract] Objective:To explore the effect of high⁃fat diet on delayed pleural effusion after single⁃port video⁃assisted thoracoscopic
lung surgery. Methods:A retrospective analysis was conducted on the clinical data of 571 patients who underwent single⁃port video⁃
assisted thoracoscopic lung surgery at the Department of Thoracic Surgery,Nanjing Medical University Affiliated Brain Hospital from
December 2021 to June 2023. Patients were divided into a high ⁃ fat diet group and a non ⁃ high ⁃ fat diet(control)group based on
postoperative dietary habits. Propensity score matching analysis was used to match the two groups of patients with a ratio of 1∶1,and
then the incidence of delayed pleural effusion and other postoperative complications was compared between the matched groups.
Results:Before matching,the high⁃fat diet group included 166 patients,with 45 males and 121 females,and an age of 56.0(49.0,
66.0)years. The control group included 405 patients,with 164 males and 241 females,and an age of 57.0(48.0,67.0)years. After
propensity score matching,each group included 130 patients. The high⁃fat diet group showed significantly higher incidences of delayed
pleural effusion(OR=1.080,95%CI:1.013-1.152,P=0.019),postoperative cough(OR=1.203,95% CI:1.091-1.326,P=0.001),and
postoperative chest tightness(OR=1.166,95%CI:1.038-1.311,P=0.010) compared to the control group,with statistically significant
differences. Conclusion:A high⁃fat diet after single⁃port thoracoscopic lung surgery can significantly increase the incidence of delayed
pleural effusion.
[Key words] single⁃port thoracoscopic surgery;pleural effusion;high⁃fat diet;propensity score matching
[J Nanjing Med Univ,2025,45(11):1662⁃1669]
[基金项目] 南京市卫生科技发展专项资金(YKK23148);南京医科大学科技发展基金(NMUB20240191)
通信作者(Corresponding author),E⁃mail:wangqin1985winny@163.com(ORCID:0000⁃0002⁃1899⁃9444)
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