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第45卷第11期      林书慧,钱萌森,朱 静,等. METTL3介导的KIF11 mRNA m6A修饰通过PI3K/AKT信号通路促进结
                 2025年11月              直肠癌进展[J]. 南京医科大学学报(自然科学版),2025,45(11):1546-1562                  ·1561 ·


                    526                                                colorectal cancer proliferation and metastasis by activat⁃
               [6] CHEN D L,WANG J H,LI Y,et al. LncRNA NEAT1 sup⁃     ing STAT3[J]. J Transl Med,2023,21(1):418
                    presses cellular senescence in hepatocellular carcinoma  [19]LIU W J,ZHANG Z L,LUO X T,et al. m6A⁃mediated
                    via KIF11 ⁃ dependent repression of CDKN2A[J]. Clin  LINC02038 inhibits colorectal cancer progression via reg⁃
                    Transl Med,2023,13(9):e1418                       ulation of the FAM172A/PI3K/AKT pathway via competi⁃
               [7] ZUIDHOF H R,MÜLLER C,KORTMAN G,et al. The          tive binding with miR⁃552⁃5p[J]. Int J Oncol,2023,63
                    m6A demethylase FTO promotes C/EBPβ⁃LIP translation  (1):81
                    to perform oncogenic functions in breast cancer cells[J].  [20]BAKR M,ABD ⁃ ELMAWLA M A,ELIMAM H,et al.
                    FEBS J,2025,292(10):2688-2709                      Telomerase RNA component lncRNA as potential diag⁃
               [8] ZHU Z M,HUO F C,SHI C,et al. METTL3 ⁃ mediated      nostic biomarker promotes CRC cellular migration and
                    m6A modification of PAK6 drives cervical cancer progres⁃  apoptosis evasion via modulation of β⁃catenin protein lev⁃
                    sion through activating MAPK14[J]. Int J Biol Macromol,  el[J]. Noncoding RNA Res,2023,8(3):302-314
                    2025,309:142880                              [21]BIAN Y B,WANG Y,XU S F,et al. m6A modification of
               [9] ZOU J,SHI X,WU Z,ZUO S,et al. MRTX1133 attenu⁃      long non⁃coding RNA HNF1A⁃AS1 facilitates cell cycle
                    ates KRAS(G12D)mutated⁃colorectal cancer progression  progression in colorectal cancer via IGF2BP2 ⁃ mediated
                    through activating ferroptosis activity via METTL14/  CCND1 mRNA stabilization[J]. Cells,2022,11(19):
                    LINC02159/FOXC2 axis[J]. Transl Oncol,2025,52:     3008
                    102235                                       [22]ZENG H,HOU Y X,ZHOU X Y,et al. Cancer⁃associated
               [10]ZHOU D,TANG W W,XU Y D,et al. METTL3/YTHDF2         fibroblasts  facilitate  premetastatic  niche  formation
                    m6A axis accelerates colorectal carcinogenesis through  through lncRNA SNHG5⁃mediated angiogenesis and vas⁃
                    epigenetically suppressing YPEL5[J]. Mol Oncol,2021,  cular permeability in breast cancer[J]. Theranostics,
                    15(8):2172-2184                                    2022,12(17):7351-7370
               [11]ZHAO S,SONG P,ZHOU G,et al. METTL3 promotes the  [23]MU H Y,CHEN J Z,HUANG W J,et al. OmicShare tools:
                    malignancy of non⁃small cell lung cancer by N6⁃methyl⁃  a zero⁃code interactive online platform for biological data
                    adenosine modifying SFRP2[J]. Cancer Gene Ther,    analysis and visualization[J]. Imeta,2024,3(5):e228
                    2023,30(8):1094-1104                         [24]ZHU T Y,HONG L L,LING Z Q. Oncofetal protein
               [12]XUE L,LI J,LIN Y H,et al. m6A transferase METTL3⁃in⁃  IGF2BPs in human cancer:functions,mechanisms and
                    duced lncRNA ABHD11⁃AS1 promotes the Warburg ef⁃   therapeutic potential[J]. Biomark Res,2023,11(1):62
                    fect of non ⁃ small ⁃ cell lung cancer[J]. J Cell Physiol,  [25]WEI Y Y,JIANG Y Z,ZOU F,et al. Activation of PI3K/
                    2021,236(4):2649-2658                              Akt pathway by CD133⁃p85 interaction promotes tumori⁃
               [13]WANG J Y,CHEN L J,QIANG P. The role of IGF 2BP2,    genic capacity of glioma stem cells[J]. Proc Natl Acad
                    an m6A reader gene,in human metabolic diseases and  Sci USA,2013,110(17):6829-6834
                    cancers[J]. Cancer Cell Int,2021,21(1):99    [26]ZHU Y L,YU J W,WANG S L,et al. Overexpression of
               [14]WANG J Y,ZHU M X,ZHU J H,et al. HES1 promotes       CD133 enhances chemoresistance to 5⁃fluorouracil by ac⁃
                    aerobic glycolysis and cancer progression of colorectal  tivating the PI3K/Akt/p70S6K pathway in gastric cancer
                    cancer via IGF2BP2⁃mediated GLUT1 m6A modification[J].  cells[J]. Oncol Rep,2014,32(6):2437-2444
                    Cell Death Discov,2023,9(1):411              [27]ZHU M,YU R,LIU Y,et al. LncRNA H19 participates in
               [15]HU X G,PENG W X,ZHOU H X,et al. IGF2BP2 regu⁃       leukemia inhibitory factor mediated stemness promotion
                    lates DANCR by serving as an N6 ⁃ methyladenosine  in colorectal cancer cells[J]. Biochem Genet,2024,62
                    reader[J]. Cell Death Differ,2020,27(6):1782⁃1794  (5):3695-3708
               [16]BARZEGAR BEHROOZ A,SYAHIR A,AHMAD S.          [28]DIEFENBACH R J,MACKAY J P,ARMATI P J,et al.
                    CD133:beyond a cancer stem cell biomarker[J]. J Drug  The C⁃terminal region of the stalk domain of ubiquitous
                    Target,2019,27(3):257-269                          human kinesin heavy chain contains the binding site for
               [17]ZHU Y L,KONG F F,ZHANG C H,et al. CD133 medi⁃       kinesin light chain[J]. Biochemistry,1998,37(47):
                    ates the TGF ⁃ β1 ⁃ induced activation of the PI3K/ERK/  16663-16670
                    P70S6K signaling pathway in gastric cancer cells[J]. On⁃  [29]LUCANUS A J,YIP G W. Kinesin superfamily:roles in
                    col Lett,2017,14(6):7211-7216                      breast cancer,patient prognosis and therapeutics[J]. On⁃
               [18]SHI Q,HE Y,HE S Y,et al. RP11⁃296E3.2 acts as an im⁃  cogene,2018,37(7):833-838
                    portant molecular chaperone for YBX1 and promotes  [30]SHARP D J,ROGERS G C,SCHOLEY J M. Microtubule
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