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microenvironment :new findings and future perspec⁃ anisms of metabolic reprogramming of tumor microenvi⁃
tives[J]. Mol Cancer,2021,20(1):131 ronment for immunotherapy in gastric cancer[J]. Cell
[14]LI Y M,HU X D,LIN R C,et al. Single⁃cell landscape re⁃ Death Dis,2022,13(4):378
veals active cell subtypes and their interaction in the tu⁃ [26]JANJIGIAN Y Y,SHITARA K,MOEHLER M,et al. First
mor microenvironment of gastric cancer[J]. Theranostics, ⁃line nivolumab plus chemotherapy versus chemotherapy
2022,12(8):3818-3833 alone for advanced gastric,gastro⁃oesophageal junction,
[15]LI X C,SUN Z,PENG G X,et al. Single⁃cell RNA se⁃ and oesophageal adenocarcinoma(CheckMate 649):a
quencing reveals a pro⁃invasive cancer⁃associated fibro⁃ randomised,open⁃label,phase 3 trial[J]. Lancet,2021,
blast subgroup associated with poor clinical outcomes in 398(10294):27-40
patients with gastric cancer[J]. Theranostics,2022,12 [27]FAN Y B,LI Y,YAO X D,et al. Epithelial SOX9 drives
(2):620-638 progressionandmetastasesofgastricadenocarcinomabypro⁃
[16]LIU Y D,LI C F,LU Y P,et al. Tumor microenvironment⁃ moting immunosuppressive tumour microenvironment[J].
mediated immune tolerance in development and treat⁃ Gut,2023,72(4):624-637
ment of gastric cancer[J]. Front Immunol,2022,13: [28]PARK S,KARALIS J D,HONG C J,et al. ACTA2 expres⁃
1016817 sion predicts survival and is associated with response to
[17]WANG B,ZHANG Y Y,QING T,et al. Comprehensive immune checkpoint inhibitors in gastric cancer[J]. Clin
analysis of metastatic gastric cancer tumour cells using Cancer Res,2023,29(6):1077-1085
single⁃cell RNA⁃seq[J]. Sci Rep,2021,11(1):1141 [29]ZHANG P R,GU Y,WANG J T,et al. Complement recep⁃
[18]HUANG X Z,PANG M J,LI J Y,et al. Single⁃cell se⁃ tor C5aR1 blockade reprograms tumor⁃associated macro⁃
quencing of ascites fluid illustrates heterogeneity and ther⁃ phages and synergizes with anti⁃PD⁃1 therapy in gastric
apy ⁃ induced evolution during gastric cancer peritoneal cancer[J]. Int J Cancer,2023,153(1):224-237
metastasis[J]. Nat Commun,2023,14(1):822 [30]YANG L,YING X J,LIU S,et al. Gastric cancer:epidemi⁃
[19]ZHANG J Z,WANG H,TIAN Y,et al. Discovery of a nov⁃ ology,risk factors and prevention strategies[J]. Chin J
el lipid metabolism⁃related gene signature to predict out⁃ Cancer Res,2020,32(6):695-704
comes and the tumor immune microenvironment in gastric [31]DENG G H,ZHANG X,CHEN Y L,et al. Single⁃cell tran⁃
cancer by integrated analysis of single⁃cell and bulk RNA scriptome sequencing reveals heterogeneity of gastric can⁃
sequencing[J]. Lipids Health Dis,2023,22(1):212 cer:progress and prospects[J]. Front Oncol,2023,13:
[20]HU J W,YANG Y P,MA Y C,et al. Survival benefits 1074268
from neoadjuvant treatment in gastric cancer:a systematic [32]SUN J R,KONG C F,YE Y X,et al. Integrated analysis of
review and meta⁃analysis[J]. Syst Rev,2022,11(1): single⁃cell and bulk RNA⁃sequencing reveals a novel sig⁃
136 nature based on NK cell marker genes to predict progno⁃
[21]MARIN J J G,PEREZ⁃SILVA L,MACIAS R I R,et al. sis and immunotherapy response in gastric cancer[J]. Sci
Molecular bases of mechanisms accounting for drug resis⁃ Rep,2024,14(1):7648
tance in gastric adenocarcinoma[J]. Cancers,2020,12 [33]LI Z P,CHEN H,CHEN Z Q,et al. Bioinformatics analy⁃
(8):2116 sis reveals prognostic significance of the macrophage
[22]YIN H H,SUN L L,YUAN Y,et al. PPIC⁃labeled CAFs: marker gene signature in gastric adenocarcinoma[J].
key players in neoadjuvant chemotherapy resistance for Front Biosci,2024,29(5):172
gastric cancer[J]. Transl Oncol,2024,48:102080 [34]CAI X,YANG J R,GUO Y S,et al. Re⁃analysis of single
[23]LU Y F,JIN Z J,HOU J Y,et al. Calponin 1 increases cell and spatial transcriptomics data reveals B cell land⁃
cancer⁃associated fibroblasts⁃mediated matrix stiffness to scape in gastric cancer microenvironment and its poten⁃
promote chemoresistance in gastric cancer[J]. Matrix Bi⁃ tial crosstalk with tumor cells for clinical prognosis[J]. J
ol,2023,115:1-15 Transl Med,2024,22(1):807
[24]JIA X Y,LI Z T,ZHOU R Y,et al. Single cell and bulk [35]WANG S,SUN S T,ZHANG X Y,et al. The evolution of
RNA sequencing identifies tumor microenvironment sub⁃ single⁃cell RNA sequencing technology and application:
+
types and chemoresistance⁃related IGF1 cancer⁃associat⁃ progress and perspectives[J]. Int J Mol Sci,2023,24(3):
ed fibroblast in gastric cancer[J]. Biochim Biophys Acta 2943
Mol Basis Dis,2024,1870(4):167123 [收稿日期] 2024-08-27
[25]ZHAO L,LIU Y Y,ZHANG S M,et al. Impacts and mech⁃ (本文编辑:陈汐敏)

