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第45卷第6期                           南京医科大学学报(自然科学版)
                  2025年6月                   Journal of Nanjing Medical University(Natural Sciences)     ·863 ·


               ·临床研究·

                冠状动脉CT血管造影的三维重建图像在非体外循环冠状动脉

                旁路移植术术前规划中的应用



                段书朋,余 万,耿          乐,陈爱东,魏 磊       *

                南京医科大学第一附属医院心脏大血管外科,江苏                  南京 210029



               [摘   要] 目的:评价冠状动脉CT血管造影(coronary CT angiography,CCTA)及其三维重建图像对非体外循环冠状动脉旁路
                移植术(off⁃pump coronary artery bypass grafting,OPCABG)术前规划的临床效果。方法:回顾性分析南京医科大学第一附属医
                院心脏大血管外科 2021 年 1 月—2023 年 3 月行 OPCABG 的 158 例患者的临床资料,其中 113 例常规采用冠状动脉造影(coro⁃
                nary angiography,CAG)指导OPCABG(常规组),45例在CAG的基础上完善CCTA检查及三维图像重建辅助OPCABG(3D组),
                对两项影像学检查结果进行综合分析并指导手术。观察指标包括手术时间、术中失血量、术后呼吸机使用时间、术后监护时间
                和住院时间、术后房颤、急性肾损伤、二次气管插管、脑梗死或心血管不良事件等并发症,以及术后1年心脏超声和CCTA随访
                结果。结果:两组术后呼吸机使用时间、术后监护时间和住院时间、术后 1 年 CCTA 及心脏超声随访结果差异无统计学意义
               (P > 0.05)。但3D组手术时间(250.7±41.4)min与常规组手术时间(271.0±57.2)min比较,差异有统计学意义(P < 0.05),3D组
                术中失血量少于常规组(P < 0.05)。结论:与常规采用CAG指导OPCABG相比,增加CCTA检查可以缩短手术时间,减少术中
                出血量,获得更好的手术效果。
               [关键词] 冠状动脉CT血管成像;三维重建;循环冠状动脉旁路移植术
               [中图分类号] R654.2;R816.2            [文献标志码] A                       [文章编号] 1007⁃4368(2025)06⁃863⁃06
                doi:10.7655/NYDXBNSN250034


                The application of three⁃dimensional reconstruction images of coronary CT angiography
                in preoperative planning of off⁃pump coronary artery bypass grafting

                DUAN Shupeng,YU Wan,GENG Le,CHEN Aidong,WEI Lei    *
                Department of Cardiovascular Surgery,the First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,
                China


               [Abstract] Objective:To evaluate the clinical effect of three⁃dimensional(3D)reconstruction images of coronary CT angiography
               (CCTA)in preoperative planning of off⁃pump coronary artery bypass grafting(OPCABG). Methods:The clinical data of 158 patients
                who underwent OPCABG from January 2021 to March 2023 in the department of cardiovascular surgery of the First Affiliated Hospital
                of Nanjing Medical University were retrospectively analyzed. Among them,113 patients underwent OPCABG guided by coronary
                angiography(CAG)(conventional group). On the basis of CAG,CCTA and 3D reconstruction of images were completed in 45 cases to
                assist OPCABG(3D group),and the operation was guided by comprehensive analysis of the results of the two imaging examinations.
                The outcome measures included operation time,intraoperative blood loss,ventilator usage time,postoperative monitoring period and
                hospital stay,postoperative atrial fibrillation,acute kidney injury,secondary tracheal intubation,cerebral infarction,cardiovascular
                adverse events and other complications,and 1 year postoperative cardiac ultrasound and CCTA follow⁃up results. Results:There was
                no significant difference between the two groups in the ventilator usage time,the postoperative monitoring period,the time of hospital
                stay,and the results of CCTA and cardiac ultrasound follow⁃up 1 year after surgery(P > 0.05). However,the operation time of the 3D
                group was(250.7 ± 41.4)min and the conventional group was(271.0 ± 57.2)min,and the differences between the two groups were
                statistically significant(P < 0.05). Moreover,the amount of blood loss during the 3D group was less than that of the conventional group


               [基金项目] 江苏省科技厅重点研发项目(BE2023081)
                通信作者(Corresponding author),E⁃mail:weileijs@163.com(ORCID:0000⁃0002⁃6493⁃4035)
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