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第46卷第1期 李圆圆,杨 杨,李万春,等. 大血管闭塞性急性缺血性卒中患者血管内治疗术后预后不良
2026年1月 预测模型的构建及价值分析[J]. 南京医科大学学报(自然科学版),2026,46(1):68-76 · 75 ·
分、入院时 NLR、入院时 ASPECT 评分、发病至再通 systematic review and meta ⁃ analysis[J]. Arq Neurop⁃
时间、mTICI 分级,基于 Logistic 构建的回归模型经 siquiatr,2024,82(4):1-7
价值评价和外部验证发现,该模型拟合度良好,且 [4] LAN X Y,LI D,CUI Y,et al. Proteomic analysis of jugular
预测价值较高,可为临床预测LVO⁃AIS 患者EVT术 venous blood in acute large vessel occlusion stroke with
futile recanalization[J]. J Cereb Blood Flow Metab,2024,
后90 d预后提供参考。
44(5):702-711
综上所述,临床因素高血压、入院时 NHISS 评
[5] GALECIO⁃CASTILLO M,FAROOQUI M,GUERRERO
分、入院时NLR、入院时ASPECT评分及治疗相关指
W R,et al. Endovascular treatment of patients with acute
标发病至再通时间、mTICI 分级均与 LVO⁃AIS 患者
ischemic stroke with tandem lesions presenting with
EVT术后90 d预后有关,基于各指标构建的Logistic low Alberta stroke program early computed tomography
回归模型具有较好的拟合度及预测价值,可为临床 score[J]. J Am Heart Assoc,2024,13(22):e035977
预测 EVT 术后 90 d 预后提供参考。与其他研究相 [6] JIANG P,ZHANG S,YU W T,et al. Late endovascular
比,本研究未局限于单一临床评分或使用血清学指 treatment for ischemic stroke with moderate to large
标预测患者预后,而是由患者自身病情出发,选取 infarct volume is associated with a better clinical progno⁃
相关影响因素预测预后,希望未来能够开展前瞻性 sis[J]. Curr Neurovasc Res,2025,21(5):564-573
研究,以协助本研究结果应用于临床。 [7] SIEGLER J E,KONERU M,QURESHI M M,et al.
利益冲突声明: CLEAR thrombectomy score:an index to estimate the
probability of good functional outcome with or without
所有作者声明无利益冲突。
Conflict of Interests: endovascular treatment in the late window for anterior
circulation occlusion[J]. J Am Heart Assoc,2024,13(14):
All authors declare no conflict of interests.
作者贡献声明: e034948
李圆圆负责研究设计、数据收集、数据分析、论文撰写全 [8] CHENG X Q,CAI W,LI C Y,et al. Imaging⁃based brain
frailty predicts unfavorable outcomes in acute ischemic
过程深度参与;杨杨参与制定研究计划、论文撰写以及对整
个研究工作负责;李万春、冯文献负责数据分析指导及论文 stroke[J]. J Am Heart Assoc,2025,14(12):e039790
[9] 中华医学会神经病学分会,中华医学会神经病学分会
撰写指导;康霞、李丹负责部分样本数据分析。
脑血管病学组,中华医学会神经病学分会神经血管介
Author’s Contributions:
入协作组.中国急性缺血性脑卒中早期血管内介入诊疗
LI Yuanyuan was deeply involved in the whole process of
study design,data collection,data analysis,and paper writing; 指南2018[J]. 中华神经科杂志,2018,51(9):683-691
YANG Yang participated in research planning, paper writing, The Neurology Branch of the Chinese Medical Associa⁃
tion,the Cerebrovascular Disease Group of the Neurology
and oversaw the entire research work;LI Wanchun and FENG
Branch of the Chinese Medical Association,the Neurovas⁃
Wenxian were responsible for guidance of data analysis and
cular Intervention Collaboration Group of the Neurology
paper writing;KANG Xia and LI Dan were responsible for part
Branch of the Chinese Medical Association. Guidelines
of sample data analysis.
for early intravascular intervention diagnosis and treat⁃
[参考文献]
ment of acute ischemic stroke in China 2018[J]. Chinese
[1] KAESMACHER J,CAVALCANTE F,KAPPELHOF M, Journal of Neurology,2018,51(9):683-691
et al. Time to treatment with intravenous thrombolysis [10] BU J Y,HAN X F,WU Y K,et al. Correlation between
before thrombectomy and functional outcomes in acute asymmetrical vein sign of SWI and long ⁃ term clinical
ischemic stroke:a meta ⁃ analysis[J]. JAMA,2024,331 outcomes in patients with middle cerebral artery ischemic
(9):764-777 stroke[J]. Jpn J Radiol,2024,42(10):1122-1129
[2] GAO F,TONG X,JIA B X,et al. Bailout intracranial [11]KNOTT M,HOELTER P,HOCK S,et al. Can flat⁃detector
angioplasty or stenting following thrombectomy for acute CT after successful endovascular treatment predict long ⁃
large vessel occlusion in China(ANGEL ⁃ REBOOT):a term outcome in patients with large vessel occlusion?An
multicentre,open ⁃ label,blinded ⁃ endpoint,randomised Alberta stroke programme early CT score⁃based study[J].
controlled trial[J]. Lancet Neurol,2024,23(8):797-806 Neurol Sci,2023,44(4):1193-1200
[3] SANTOS A C F F,COELHO L L S,CALDAS G C,et al. [12] ELAWADY S S,SAWAY B F,MATSUKAWA H,et al.
General anesthesia versus conscious sedation in mechani⁃ Thrombectomy in stroke patients with low Alberta stroke
cal thrombectomy for patients with acute ischemic stroke: program early computed tomography score:is modified

