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第46卷第1期          李圆圆,杨    杨,李万春,等. 大血管闭塞性急性缺血性卒中患者血管内治疗术后预后不良
                  2026年1月          预测模型的构建及价值分析[J]. 南京医科大学学报(自然科学版),2026,46(1):68-76                   · 75   ·


                分、入院时 NLR、入院时 ASPECT 评分、发病至再通                          systematic review and meta ⁃ analysis[J]. Arq Neurop⁃
                时间、mTICI 分级,基于 Logistic 构建的回归模型经                       siquiatr,2024,82(4):1-7
                价值评价和外部验证发现,该模型拟合度良好,且                           [4] LAN X Y,LI D,CUI Y,et al. Proteomic analysis of jugular
                预测价值较高,可为临床预测LVO⁃AIS 患者EVT术                            venous blood in acute large vessel occlusion stroke with
                                                                       futile recanalization[J]. J Cereb Blood Flow Metab,2024,
                后90 d预后提供参考。
                                                                       44(5):702-711
                    综上所述,临床因素高血压、入院时 NHISS 评
                                                                 [5] GALECIO⁃CASTILLO M,FAROOQUI M,GUERRERO
                分、入院时NLR、入院时ASPECT评分及治疗相关指
                                                                       W R,et al. Endovascular treatment of patients with acute
                标发病至再通时间、mTICI 分级均与 LVO⁃AIS 患者
                                                                       ischemic stroke with tandem lesions presenting with
                EVT术后90 d预后有关,基于各指标构建的Logistic                         low Alberta stroke program early computed tomography
                回归模型具有较好的拟合度及预测价值,可为临床                                 score[J]. J Am Heart Assoc,2024,13(22):e035977
                预测 EVT 术后 90 d 预后提供参考。与其他研究相                     [6] JIANG P,ZHANG S,YU W T,et al. Late endovascular
                比,本研究未局限于单一临床评分或使用血清学指                                 treatment for ischemic stroke with moderate to large
                标预测患者预后,而是由患者自身病情出发,选取                                 infarct volume is associated with a better clinical progno⁃
                相关影响因素预测预后,希望未来能够开展前瞻性                                 sis[J]. Curr Neurovasc Res,2025,21(5):564-573
                研究,以协助本研究结果应用于临床。                                [7] SIEGLER J E,KONERU M,QURESHI M M,et al.
                   利益冲突声明:                                             CLEAR thrombectomy score:an index to estimate the
                                                                       probability of good functional outcome with or without
                   所有作者声明无利益冲突。
                   Conflict of Interests:                              endovascular treatment in the late window for anterior
                                                                       circulation occlusion[J]. J Am Heart Assoc,2024,13(14):
                   All authors declare no conflict of interests.
                   作者贡献声明:                                             e034948
                   李圆圆负责研究设计、数据收集、数据分析、论文撰写全                     [8] CHENG X Q,CAI W,LI C Y,et al. Imaging⁃based brain
                                                                       frailty predicts unfavorable outcomes in acute ischemic
                过程深度参与;杨杨参与制定研究计划、论文撰写以及对整
                个研究工作负责;李万春、冯文献负责数据分析指导及论文                             stroke[J]. J Am Heart Assoc,2025,14(12):e039790
                                                                 [9] 中华医学会神经病学分会,中华医学会神经病学分会
                撰写指导;康霞、李丹负责部分样本数据分析。
                                                                       脑血管病学组,中华医学会神经病学分会神经血管介
                   Author’s Contributions:
                                                                       入协作组.中国急性缺血性脑卒中早期血管内介入诊疗
                   LI Yuanyuan was deeply involved in the whole process of
                study design,data collection,data analysis,and paper writing;  指南2018[J]. 中华神经科杂志,2018,51(9):683-691
                YANG Yang participated in research planning, paper writing,  The Neurology Branch of the Chinese Medical Associa⁃
                                                                       tion,the Cerebrovascular Disease Group of the Neurology
                and oversaw the entire research work;LI Wanchun and FENG
                                                                       Branch of the Chinese Medical Association,the Neurovas⁃
                Wenxian were responsible for guidance of data analysis and
                                                                       cular Intervention Collaboration Group of the Neurology
                paper writing;KANG Xia and LI Dan were responsible for part
                                                                       Branch of the Chinese Medical Association. Guidelines
                of sample data analysis.
                                                                       for early intravascular intervention diagnosis and treat⁃
               [参考文献]
                                                                       ment of acute ischemic stroke in China 2018[J]. Chinese
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                    et al. Time to treatment with intravenous thrombolysis  [10] BU J Y,HAN X F,WU Y K,et al. Correlation between
                    before thrombectomy and functional outcomes in acute  asymmetrical vein sign of SWI and long ⁃ term clinical
                    ischemic stroke:a meta ⁃ analysis[J]. JAMA,2024,331  outcomes in patients with middle cerebral artery ischemic
                    (9):764-777                                        stroke[J]. Jpn J Radiol,2024,42(10):1122-1129
               [2] GAO F,TONG X,JIA B X,et al. Bailout intracranial  [11]KNOTT M,HOELTER P,HOCK S,et al. Can flat⁃detector
                    angioplasty or stenting following thrombectomy for acute  CT after successful endovascular treatment predict long ⁃
                    large vessel occlusion in China(ANGEL ⁃ REBOOT):a  term outcome in patients with large vessel occlusion?An
                    multicentre,open ⁃ label,blinded ⁃ endpoint,randomised  Alberta stroke programme early CT score⁃based study[J].
                    controlled trial[J]. Lancet Neurol,2024,23(8):797-806  Neurol Sci,2023,44(4):1193-1200
               [3] SANTOS A C F F,COELHO L L S,CALDAS G C,et al.  [12] ELAWADY S S,SAWAY B F,MATSUKAWA H,et al.
                    General anesthesia versus conscious sedation in mechani⁃  Thrombectomy in stroke patients with low Alberta stroke
                    cal thrombectomy for patients with acute ischemic stroke:  program early computed tomography score:is modified
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