Page 120 - 《南京医科大学学报》自然科学版2026年第2期
P. 120

第46卷第2期
               ·276 ·                            南 京    医 科 大 学 学         报                        2026年2月


              可能为眼脑退行性疾病的治疗开辟新思路。                                    Ophthalmic Res,2021,64(3):345-355
                  利益冲突声明:                                       [11]SCHLECHT A,VALLON M,WAGNER N,et al. TGFβ⁃
                  所有作者声明无利益冲突。                                       neurotrophin interactions in heart,retina,and brain[J].
                  Conflict of Interests:                             Biomolecules,2021,11(9):1360
                  The authors declare no conflict of interests.  [12]FALABELLA M,VERNON H J,HANNA M G,et al. Car⁃
                  作者贡献声明:                                            diolipin,mitochondria,and neurological disease[J].
                  杭昊负责论文撰写和修改,高俊英参与论文审阅与论文                           Trends Endocrinol Metab,2021,32(4):224-237
              修改,曹秋晨负责研究的整体规划和设计,对全文进行了审                        [13]ASHOK A,SINGH N,CHAUDHARY S,et al. Retinal de⁃
              阅和修改。                                                  generation and Alzheimer’s disease:an evolving link[J].
                  Author’s Contributions:                            Int J Mol Sci,2020,21(19):7290
                  HANG Hao was responsible for the writing and revision of  [14]BAUDOUIN C,KOLKO M,MELIK ⁃ PARSADANIANTZ
              the paper. GAO Junying reviewed and revised the paper. CAO  S,et al. Inflammation in glaucoma:from the back to the
                                                                     front of the eye,and beyond[J]. Prog Retin Eye Res,
              Qiuchen was in charge of the overall planning and design of the
              study,and reviewed and revised the paper.              2021,83:100916
                                                                [15]KLYUCHEREV T O,OLSZEWSKI P,SHALIMOVA A A,
             [参考文献]
                                                                     et al. Advances in the development of new biomarkers for
             [1] ZHAO B X,LI Y J,FAN Z R,et al. Eye⁃brain connec⁃    Alzheimer’s disease[J]. Transl Neurodegener,2022,11
                   tions revealed by multimodal retinal and brain imaging ge⁃  (1):25
                   netics[J]. Nat Commun,2024,15(1):6064        [16]GAIRE B P,KORONYO Y,FUCHS D T,et al. Alzhei⁃
             [2] KERSCHENSTEINER D,FELLER M B. Mapping the           mer’s disease pathophysiology in the retina[J]. Prog
                   retina onto the brain[J]. Cold Spring Harb Perspect Biol,  Retin Eye Res,2024,101:101273
                   2024,16(2):a041512                           [17]YIN X Y,ZHANG S,LEE J H,et al. Compartmentalized
             [3] MARCHESI N,FAHMIDEH F,BOSCHI F,et al. Ocular        ocular lymphatic system mediates eye⁃brain immunity[J].
                   neurodegenerative diseases:interconnection between reti⁃  Nature,2024,628(8006):204-211
                   na and cortical areas[J]. Cells,2021,10(9):2394  [18]CAO Q C,YANG S G,WANG X W,et al. Transport of
             [4] ALVES J N,WESTNER B U,HØJLUND A,et al. Struc⁃       β ⁃amyloid from brain to eye causes retinal degeneration
                   tural and functional changes in the retina in Parkinson’s  in Alzheimer’s disease[J]. J Exp Med,2024,221(11):
                   disease[J]. J Neurol Neurosurg Psychiatry,2023,94(6):  e20240386
                   448-456                                      [19]WANG X W,LOU N H,EBERHARDT A,et al. An ocu⁃
             [5] GRAFF⁃RADFORD J,YONG K X X,APOSTOLOVA L             lar glymphatic clearance system removes β⁃amyloid from
                   G,et al. New insights into atypical Alzheimer’s disease  the rodent eye[J]. Sci Transl Med,2020,12(536):
                   in the era of biomarkers[J]. Lancet Neurol,2021,20(3):  eaaw3210
                   222-234                                      [20]GUYMER R H,CAMPBELL T G. Age⁃related macular de⁃
             [6] MARAN J J,ADESINA M M,GREEN C R,et al. The cen⁃     generation[J]. Lancet,2023,401(10386):1459-1472
                   tral role of the NLRP3 inflammasome pathway in the  [21]WEN L Y,WAN L,LAI J N,et al. Increased risk of
                   pathogenesis of age ⁃ related diseases in the eye and the  Alzheimer’s disease among patients with age⁃related mac⁃
                   brain[J]. Ageing Res Rev,2023,88:101954           ular degeneration:a nationwide population⁃based study[J].
             [7] SEMENOVA Y,BJØRKLUND G. Antioxidants and neuro⁃     PLoS One,2021,16(5):e0250440
                   degenerative eye disease[J]. Crit Rev Food Sci Nutr,  [22]LEE C S,LARSON E B,GIBBONS L E,et al. Associa⁃

                   2024,64(26):9672-9690                             tions between recent and established ophthalmic condi⁃
             [8] JAYARAM H,KOLKO M,FRIEDMAN D S,et al. Glau⁃         tions and risk of Alzheimer’s disease[J]. Alzheimers
                   coma:now and beyond[J]. Lancet,2023,402(10414):   Dement,2019,15(1):34-41
                   1788-1801                                    [23]NAKAMURA K,TAN F,LI Z J,et al. NGF activation of
             [9] TAN T N,WONG T Y. Diabetic retinopathy:looking for⁃  TrkA induces vascular endothelial growth factor expres⁃
                   ward to 2030[J]. Front Endocrinol(Lausanne),2023,13:  sion via induction of hypoxia⁃inducible factor⁃1α[J]. Mol
                   1077669                                           Cell Neurosci,2011,46(2):498-506
             [10]FUDALEJ E,JUSTYNIARSKA M,KASAREŁŁO K,et al.    [24]INANC T M,SEKEROGLU M A,DEMIRTAS C,et al.
                   Neuroprotective factors of the retina and their role in pro⁃  Brain⁃derived neurotrophic factor in patients with age⁃re⁃
                   moting survival of retinal ganglion cells:a review[J].  lated macular degeneration and its correlation with retinal
   115   116   117   118   119   120   121   122   123   124   125