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第46卷第3期
               ·328 ·                            南 京    医 科 大 学 学         报                        2026年3月


                                  表3 CR组和N⁃CR组化疗前后腰椎MRI定量参数变化及临床指标比较
              Table 3 Comparison of quantitative parameters and clinical indicators of lumbar spine MRI before and after chemotherapy
                      in the CR group and N⁃CR group

                              Indicator                   N⁃CR group(n=25)         CR group(n=54)         P
               Sex[n(%)]                                                                                 0.375
                 Male                                         11(44.0)                32(59.3)
                 Female                                       14(56.0)                22(40.7)
               Age[months,M(P25,P75 )]                       48(36,60)               48(36,108)          0.395
               Risk factor[n(%)]                                                                       < 0.001
                 Low⁃risk                                      3(12.0)                 5(20.9)
                 Medium⁃risk                                  21(84.0)                40(74.1)
                 High⁃risk                                     1(4.0)                  9(6.0)
               LDH[U/L,M(P25,P75 )]                    1 107.40(497.63,1 717.16)  1 172.50(701.04,1 643.96)  0.861
               WBC[×10 ,M(P25,P75 )]                       15.18(5.31,25.07)       27.43(5.78,49.08)     0.299
                       9
               Primitive naive lymphocytes(%,x ± s)          84.12 ± 12.91           80.04 ± 15.48       0.294
               Before chemotherapy PDFF[%,M(P25,P75 )]     3.06(1.90,3.66)          3.00(2.07,3.79)      0.601
               After chemotherapy PDFF(%,x ± s)              25.83 ± 14.21           37.47 ± 15.63       0.005
               Before chemotherapy R2(S ,x ± s)              84.29 ± 14.52           91.45 ± 26.23       0.197
                                 *
                                   -1
               After chemotherapy R2[S ,M(P25,P75 )]     110.08(99.67,158.05)    158.66(140.62,172.43)   0.008
                                *
                                  -1
               Before chemotherapy f(x ± s)                  0.49 ± 0.15             0.52 ± 0.10         0.432
               After chemotherapy f(x ± s)                   0.45 ± 0.14              0.49± 0.09         0.198
               Before chemotherapy D[×10 mm /s,M(P25,P75 )]  0.28(0.33,0.52)        0.41(0.26,0.34)      0.024
                                        2
                                    -3
               After chemotherapy D[×10 mm /s,M(P25,P75 )]  0.34(0.22,0.61)         0.30(0.25,0.34)      0.116
                                   -3
                                       2
               Before chemotherapy D[×10 mm /s,M(P25,P75 )]  49.16(44.48,73.42)  115.98(36.40,195.57)    0.030
                                        2
                                *
                                    -3
               After chemotherapy D[×10 mm /s,M(P25,P75 )]  108.02(36.95,179.09)  57.74(44.40,71.00)     0.163
                               *
                                   -3
                                       2
                       A                                          B    300
                             (%)  60                                  (S -1 )  250
                             Afer chemotherapy PDFF  40               Afer chemotherapy R2 *  200
                                                                       150
                              20
                               0                                       100
                                                                        50
                                   CR group(n=25) N⁃CR group(n=54)          CR group(n=25) N⁃CR group(n=54)
                           mm 2 /s)  1 000                           (×10 -3 mm 2 /s)  1 000
                       C                                         D
                           (×10 -3  800                                800

                           Before chemotherapy D  400                Before chemotherapy D *  400
                             600
                                                                       600

                             200
                                                                       200
                               0
                                   CR group(n=25) N⁃CR group(n=54)      0   CR group(n=25) N⁃CR group(n=54)

                                                                             *
                 A:ComparisonofPDFFbetweentheCRandN⁃CRgroupsafterchemotherapy.B:ComparisonofR2 betweentheCRandN⁃CRgroupsafterchemotherapy.
                                                                         *
              C:Comparison of D between the CR and N⁃CR groups before chemotherapy. D:Comparison of D between the CR and N⁃CR groups before chemotherapy.
                                 图3   化疗后PDFF及R2 、化疗前D及D 在CR组与N⁃CR组的分布箱式图
                                                     *
                                                                 *
              Figure 3 Box plot of PDFF and R2 after chemotherapy and D and D before chemotherapy in the CR group and N⁃CR group
                                          *
                                                                   *
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