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·548 · 南 京 医 科 大 学 学 报 2026年4月
查提供了可避免 ICA 的关键循证工具,填补了该领 physiology,clinical implications,and therapeutic manage⁃
域无创预警体系的空白。未来研究需在多中心前瞻 ment[J]. Angiology,2021,72(9):808-818
性队列中,通过动态随访并整合炎症、症状、心电图及 [8] REHAN R,YONG A,NG M,et al. Coronary microvascu⁃
lar dysfunction:a review of recent progress and clinical
超声等多模态信息,验证并优化本模型,以建立真正
implications[J]. Front Cardiovasc Med,2023,10:
可用于临床早期预警和风险分层的无创工具。
1111721
利益冲突声明:
[9] AL⁃GULLY J,OLIVERI F,FOROUZANFAR J P,et al.
所有作者声明无利益冲突。
Prognostic role of con ⁃/discordant coronary flow reserve
Conflict of Interests:
and microvascular resistance in coronary microvascular
All the authors declare no conflict of interests.
disease:a systematic review and network meta⁃analysis[J].
作者贡献声明:
Open Heart,2025,12(1):e003055
尹燕奎负责研究设计及论文撰写;伦立民、徐龙强、侯宝
[10]ALVAREZ C,SIU H. Coronary slow⁃flow phenomenon as
煜负责试验实施及文本修改;贾丰豪、刘振负责统计学方法 an underrecognized and treatable source of chest pain:
设计;张学志负责项目管理,文章审阅。
case series and literature review[J]. J Investig Med High
Author’s Contributions:
Impact Case Rep,2018,6:2324709618789194
YIN Yankui contributed to study design and manuscript
[11]FARSI F,MOROVATDAR N,ESHRAGHI A. Baseline
drafting;LUN Limin,XU Longqiang,and HOU Baoyu conducted characteristics and seven⁃year follow⁃up of patients with
experiments and revised the manuscript;JIA Fenghao and LIU coronary slow flow:a cohort study in northeastern Iran[J].
Zhen designed statistical methodologies;ZHANG Xuezhi super⁃ J Cardiovasc Thorac Res,2025,17(1):20-26
vised the project and critically reviewed the manuscript. [12]KAPLAN M,ABACIOGLU Ö Ö,YAVUZ F,et al. Slow
[参考文献] flow phenomenon impairs the prognosis of coronary artery
ectasia as well as coronary atherosclerosis[J]. Braz J Car⁃
[1] TAMBE A A,DEMANY M A,ZIMMERMAN H A,et al.
diovasc Surg,2021,36(3):346-353
Angina pectoris and slow flow velocity of dye in coronary
[13]KOPETZ V A,PENNO M A,HOFFMANN P,et al. Po⁃
arteries ⁃ a new angiographic finding[J]. Am Heart J,
tential mechanisms of the acute coronary syndrome pre⁃
1972,84(1):66-71
sentatation in patients with the coronary slow flow phe⁃
[2] APARICIO A,CUEVAS J,MORÍS C,et al. Slow coronary
nomenon⁃insight from a plasma proteomic approach[J].
blood flow:pathogenesis and clinical implications[J].
Int J Cardiol,2012,156(1):84-91
Eur Cardiol,2022,17:e08
[14]KOPETZ V,KENNEDY J,HERESZTYN T,et al. Endo⁃
[3] MIKAEILVAND A,HAJIZADEH R,BATENI A,et al.
thelial function,oxidative stress and inflammatory studies
Long⁃term prognosis in patients with coronary slow flow[J].
in chronic coronary slow flow phenomenon patients[J].
J Tehran Heart Cent,2022,17(4):202-206
Cardiology,2012,121(3):197-203
[4] MARACLE C X,AGCA R,HELDER B,et al. Noncanoni⁃
[15]BRUYNDONCKX L,HOYMANS V Y,DE GUCHTEN⁃
cal NF⁃κB signaling in microvessels of atherosclerotic le⁃
AERE A,et al.Diet,exercise,and endothelial function in
sions is associated with inflammation,atheromatous
obese adolescents[J].Pediatrics,2015,135(3):653-661
plaque morphology and myocardial infarction[J]. Athero⁃ [16]陈 然,孟浩宇,陈 波. 冠状动脉慢血流影响因素分
sclerosis,2018,270:33-41 析[J]. 南京医科大学学报(自然科学版),2020,40(2):
[5] 贾 静,刘江波,冉 倩. 血清GDF15、IMA、Copeptin水 223-227
平联合检测急性冠脉综合征患者PCI术后心肌损伤的 CHEN R,MENG H R,CHEN B. Analysis of influencing
诊断效能[J]. 实验与检验医学,2023,41(2):207-209 factors for coronary slow flow[J]. Journal of Nanjing Medi⁃
JIA J,LIU J B,RAN Q. Combined detection of serum cal University(Natural Sciences),2020,40(2):223-227
GDF15,IMA,and copeptin levels for acute diagnostic effi⁃ [17]袁 燕,沙晓娟,马冬丽,等. 内脏脂肪指数与冠状动脉
cacy of post⁃PCI myocardial injury in patients with coro⁃ 慢血流相关性分析[J]. 中国临床医学,2023,30(5):
nary syndromes[J]. Experimental and Laboratory Medi⁃ 819-24
cine,2023,41(2):207-209 YUAN Y,SHA X J,MA D L,et al. Correlation analysis
[6] BELTRAME J F,LIMAYE S B,HOROWITZ J D. The cor⁃ between coronary slow flow and visceral adiposity index[J].
onary slow flow phenomenon⁃a new coronary microvascu⁃ Chinese Journal of Clinical Medicine,2023,30(5):819-
lar disorder[J]. Cardiology,2002,97(4):197-202 824
[7] CHALIKIAS G,TZIAKAS D. Slow coronary flow:patho⁃ [18]SANATI H,KIANI R,SHAKERIAN F,et al. Coronary

