Page 149 - 南京医科大学自然版

第46卷第8期 朱孟飞，石中华，刘志伟. 妊娠期糖尿病对子代骨骼发育影响的证据整合及机制研究进展［J］.
2026年8月 南京医科大学学报（自然科学版），2026，46（8）：1246-1257 ·1255 ·

2025，15（3）：440 longitudinal study［J］. Sci Rep，2023，13（1）：13939
［14］HOFFMAN D J，POWELL T L，BARRETT E S，et al. De⁃ ［27］MARTINE⁃EDITH G，JOHNSON W，PETHERICK E S.
velopmental origins of metabolic diseases［J］. Physiol Associations between maternal gestational diabetes met⁃
Rev，2021，101（3）：739-795 formin or insulin treatment and offspring growth trajecto⁃
［15］YAN Y S，FENG C，YU D Q，et al. Long⁃term outcomes ries from birth to 60 months of age：findings from the Born
and potential mechanisms of offspring exposed to intra⁃ in Bradford（BiB）study［J］. Diabet Med，2023，40（11）：
uterine hyperglycemia［J］. Front Nutr，2023，10：1067282 e15204
［16］ZHOU X，ZHANG H，WEI L，et al. Oxidative stress，mito⁃ ［28］FEGHALI M，ATLASS J，ABEBE K Z，et al. Treatment of
chondrial dysfunction，and ferroptosis in the placenta of gestational diabetes mellitus and offspring early child⁃
gestational diabetes mellitus［J］. J Mol Med（Berl），2025， hood growth［J］. J Clin Endocrinol Metab，2021，106（4）：
104（1）：8 e1849-e1858
［17］ARNOLD A，DENNISON E，KOVACS C S，et al. Hormonal ［29］中华医学会妇产科学分会产科学组，中华医学会围产
regulation of biomineralization［J］. Nat Rev Endocrinol， 医学分会，中国妇幼保健协会妊娠合并糖尿病专业委
2021，17（5）：261-275 员会. 妊娠期高血糖诊治指南（2022）［第一部分］［J］.
［18］KOVÁCS C S，WARD L M. Chapter 33 ⁃ Physiology of 中华妇产科杂志，2022，57（1）：3-12
calcium，phosphorus，and bone metabolism during fetal Obstetrics Subgroup，Chinese Society of Obstetrics and
and neonatal development［M］. Maternal⁃Fetal and Neo⁃ Gynecology，Chinese Medical Association，Chinese Soci⁃
natal Endocrinology. 2nd ed. Cambridge：Academic ety of Perinatal Medicine，Chinese Medical Association，
Press，2026：645-658 Commitee of Pregnancy with Diabetes Mellitus，China Ma⁃
［19］TROMPET D，MELIS S，CHAGIN A S，et al. Skeletal ternal and Child Health Association. Guideline of diagno⁃
stem and progenitor cells in bone development and sis and treatment of hyperglycemia in pregnancy（2022）
repair［J］. J Bone Miner Res，2024，39（6）：633-654 ［Part one］［J］. Chinese Journal of Obstetrics and Gyne⁃
［20］VARSHNEY S，ADELA R，KACHHAWA G，et al. Dis⁃ cology，2022，57（1）：3-12
rupted placental vitamin D metabolism and calcium ［30］KRISHNAN S，ASTON C E，FIELDS D A，et al. Bone
signaling in gestational diabetes and pre⁃eclampsia pa⁃ mass accrual in first six months of life：impact of maternal
tients［J］. Endocrine，2023，80（1）：191-200 diabetes，infant adiposity，and cord blood adipokines［J］.
［21］CHEN Z L，LIU X，TAO M Y，et al. Gestational diabetes Calcif Tissue Int，2022，111（3）：248-255
mellitus and linear growth in early childhood［J］. Front ［31］Queensland Health. Queensland clinical guideline：gesta⁃
Endocrinol（Lausanne），2024，15：1470678 tional diabetes mellitus（GDM）［Z］. 2025
［22］SHAH V N，LESLIE W D，LAUTATZIS M E，et al. Maternal ［32］LU B，ZHANG L. Association of a history of gestational di⁃
diabetes and fracture risk in offspring：a population⁃based abetes mellitus with osteoporosis，bone mineral density，
analysis［J］. J Bone Miner Res，2024，39（6）：683-687 and trabecular bone score in postmenopausal women［J］.
［23］ORNOY A，BECKER M，WEINSTEIN⁃FUDIM L，et al. Diabetol Metab Syndr，2023，15（1）：215
Diabetes during pregnancy：a maternal disease complicati⁃ ［33］ZENG Y，YIN L，YIN X，et al. Total cholesterol mediates
ng the course of pregnancy with long⁃term deleterious ef⁃ the association between history of gestational diabetes
fects on the offspring. a clinical review［J］. Int J Mol Sci， mellitus and bone mineral density in US women aged 20⁃
2021，22（6）：2965 49 years［J］. BMC Public Health，2024，24（1）：81
［24］ZHANG T N，HUANG X M，ZHAO X Y，et al. Risks of ［34］ZHANG M，MA M，WANG J，et al. Effect of gestational di⁃
specific congenital anomalies in offspring of women with abetes mellitus on the growth，development，and stem
diabetes：a systematic review and meta⁃analysis of popula⁃ cells of offspring［J］. Matern Fetal Med，2021，5（1）：31-
tion ⁃ based studies including over 80 million births［J］. 35
PLoS Med，2022，19（2）：e1003900 ［35］PANDRICH M J，SHAH N M，GARCIA PEREZ I，et al.
［25］YEFET E，JEDA E，YOSSEF A，et al. Risk for fetal mal⁃ Gestational diabetes exposed mesenchymal stem cells：
formations and unfavorable neonatal outcomes in early⁃on⁃ phenotypic differences link to long ⁃ term health of off⁃
set gestational diabetes mellitus［J］. J Endocrinol Invest， spring［J］. Int J Mol Sci，2025，26（21）：10768
2024，47（5）：1181⁃1190 ［36］Hapo Study Cooperative Research Group，METZGER B E，
［26］GUO B，PEI J，XU Y，et al. Effects of early standardized LOWE L P，et al. Hyperglycemia and adverse pregnancy
management on the growth trajectory of offspring with ges⁃ outcomes［J］. N Engl J Med，2008，358（19）：1991-2002
tational diabetes mellitus at 0⁃5 years old：a preliminary ［37］LAPPAS M，HIDEN U，DESOYE G，et al. The role of oxi⁃