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The itaconate pathway is a central regulatory node linking immunity,tolerance,priming and differentiation:distinct
innate immune tolerance and trained immunity[J]. Cell immunological processes[J]. Nat Immunol,2021,22(1):
Metab,2019,29(1):211-220 2-6
[15] ROY P,VEKEMANS J,CLARK A,et al. Potential effect [28] SÁNCHEZ⁃RAMÓN S,CONEJERO L,NETEA M G,et
of age of BCG vaccination on global paediatric tuberculo⁃ al. Trained immunity⁃based vaccines:a new paradigm for
sis mortality:a modelling study[J]. Lancet Glob Health, the development of broad⁃spectrum anti⁃infectious formu⁃
2019,7(12):1655-1663 lations[J]. Front Immunol,2018,9:2936
[16] NETEA M G,GIAMARELLOS ⁃ BOURBOULIS E J, [29] SOHRABI Y,SONNTAG G V H,BRAUN L C,et al. LXR
DOMÍNGUEZ⁃ANDRÉS J,et al. Trained immunity:a tool activation induces a proinflammatory trained innate immu⁃
for reducing susceptibility to and the severity of SARS ⁃ nity⁃phenotype in human monocytes[J]. Front Immunol,
CoV⁃2 infection[J]. Cell,2020,181(5):969-977 2020,11:353
[17] O’NEILL L A J,NETEA M G. BCG⁃induced trained im⁃ [30] SANTECCHIA I,VERNEL⁃PAUILLAC F,RASID O,et
munity:can it offer protection against COVID ⁃ 19?[J]. al. Innate immune memory through TLR2 and NOD2 con⁃
Nat Rev Immunol,2020,20(6):335-337 tributes to the control of Leptospira interrogans infection
[18] YORK A M. Tuberculosis stifles trained immunity[J]. [J]. PLoS Pathog,2019,15(5):1007811
Nat Rev Microbiol,2021,19(1):2 [31] BRAZA M S,VAN LEENT M M T,LAMEIJER M,et al.
[19] HONG M,BERTOLETTI A. Tolerance and immunity to Inhibiting inflammation with myeloid cell⁃specific nanobio⁃
pathogens in early life:insights from HBV infection[J]. logics promotes organ transplant acceptance[J]. Immuni⁃
Semin Immunopathol,2017,39(6):643-652 ty,2018,49(5):819-828
[20] YANG Y,ZHAO X,WANG Z,et al. Nuclear sensor inter⁃ [32] MOURITS V P,ARTS R J W,NOVAKOVIC B,et al. The
feron⁃inducible protein 16 inhibits the function of hepati⁃ role of Toll⁃like receptor 10 in modulation of trained im⁃
tis B virus covalently closed circular DNA by integrating munity[J]. Immunology,2020,159(3):289-297
innate immune activation and epigenetic suppression[J]. [33]DRUMMER C,SAAOUD F,SHAO Y,et al. Trained im⁃
Hepatology,2020,71(4):1154-1169 munity and reactivity of macrophages and endothelial cells
[21] IERONYMAKI E,THEODORAKIS E M,LYRONI K,et [J]. Arterioscler Thromb Vasc Biol,2021,41(3):1032-
al. Insulin resistance in macrophages alters their metabo⁃ 1046
lism and promotes an M2⁃like phenotype[J]. J Immunol, [34] GAO R Y,WANG M,LIU Q,et al. Hypoxia⁃inducible fac⁃
2019,202(6):1786-1797 tor ⁃ 2α reprograms liver macrophages to protect against
[22] IERONYMAKI E,DASKALAKI M G,LYRONI K,et al. acute liver injury through the production of interleukin⁃6
Insulin signaling and insulin resistance facilitate trained [J]. Hepatology,2020,71(6):2105-2117
immunity in macrophages through metabolic and epigene⁃ [35] SHEPPARD S,SUN J. Virus ⁃ specific NK cell memory
tic changes[J]. Front Immunol,2019,10:1330 [J]. J Exp Med,2021,218(4):e20201731. DOI:10.1084/
[23] DU L,LIN L,LI Q,et al. IGF ⁃ 2 preprograms maturing jem.20201731
macrophages to acquire oxidative phosphorylation⁃depen⁃ [36] GANG M,MARIN N D,WONG P,et al. CAR⁃modified
dent anti⁃inflammatory properties[J]. Cell Metab,2019, memory⁃like NK cells exhibit potent responses to NK⁃re⁃
29(6):1363-1375 sistant lymphomas[J]. Blood,2020,136(20):2308-2318
[24] VAN DER HEIJDEN C D C C,GROH L,KEATING S T, [37] CERWENKA A,LANIER L L. Natural killer cell memory
et al. Catecholamines induce trained immunity in mono⁃ in infection,inflammation and cancer[J]. Nat Rev Immu⁃
cytes in vitro and in vivo[J]. Circ Res,2020,127(2): nol,2016,16(2):112-123
269-283 [38] BEAULIEU A M. Transcriptional and epigenetic regula⁃
[25]VAN DER HEIJDEN C D C C,KEATING S T,GROH L, tion of memory NK cell responses[J]. Immunol Rev,
et al. Aldosterone induces trained immunity:the role of 2021,300(1):125-133
fatty acid synthesis[J]. Cardiovasc Res,2020,116(2): [39] PLACEK K,SCHULTZE J L,NETEA M G. Immune me⁃
317-328 mory characteristics of innate lymphoid cells[J]. Curr
[26] BEKKERING S,STIEKEMA L C A,BERNELOT MOENS Opin Infect Dis,2019,32(3):196-203
S,et al. Treatment with statins does not revert trained im⁃ [40] MORAL J A,LEUNG J,ROJAS L A,et al. ILC2s amplify
munity in patients with familial hypercholesterolemia[J]. PD⁃1 blockade by activating tissue⁃specific cancer immu⁃
Cell Metab,2019,30(1):1-2 nity[J]. Nature,2020,579(7797):130-135
[27] DIVANGAHI M,AABY P,KHADER S A,et al. Trained [41] KRABBENDAM L,BAL S M,SPITS H,et al. New in⁃