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第42卷第2期 胡默然,吴周璐,赵晨曦,等. 神经节苷脂 GM3在非酒精性脂肪肝炎小鼠肝脏中的表达变化[J].
2022年2月 南京医科大学学报(自然科学版),2022,42(02):153-159 ·159 ·
Int J Mol Sci,2020,21(15):5539 [27] XU H,ZHAO Q,SONG N,et al. AdipoR1/AdipoR2 dual
[20] DAM D H M,PALLER A S. Gangliosides in diabetic agonist recovers nonalcoholic steatohepatitis and related
wound healing[J]. Prog Mol Biol Transl Sci,2018,156: fibrosis via endoplasmic reticulum⁃mitochondria axis[J].
229-239 Nat Commun,2020,11(1):5807
[21] SHIMIZU T,NAGANE M,SUZUKI M,et al. Tumor hy⁃ [28] XIONG X,WANG Q,WANG S,et al. Mapping the molec⁃
poxia regulates ganglioside GM3 synthase,which contrib⁃ ular signatures of diet⁃induced NASH and its regulation
utes to oxidative stress resistance in malignant melanoma by the hepatokine Tsukushi[J]. Mol Metab,2019,20:
[J]. Biochim Biophys Acta Gen Subj,2020,1864(12):
128-137
129723
[29] ZHENG C P,TERRENI M,SOLLOGOUB M,et al. Gan⁃
[22] LALAZAR G,ZIGMOND E,WEKSLER⁃ZANGEN S,et glioside GM3 and its role in cancer[J]. Curr Med Chem,
al. Oral administration of beta ⁃ glucosylceramide for the
2019,26(16):2933-2947
treatment of insulin resistance and nonalcoholic steato⁃
[30] ZHENG C,GUAN H,LIU Y,et al. Chemoenzymatically
hepatitis:results of a double⁃blind,placebo⁃controlled tri⁃
synthesized ganglioside GM3 analogues with inhibitory ef⁃
al[J]. J Med Food,2017,20(5):458-464
fects on tumor cell growth and migration[J]. Eur J Med
[23] PARK J,KWAK C H,HA S H,et al. Ganglioside GM3
Chem,2019,165:107-114
suppresses lipopolysaccharide ⁃ induced inflammatory re⁃
[31] ZHENG C,HUANG R,BAVARO T,et al. Design,synthe⁃
sponses in rAW 264.7 macrophage cells through NF⁃kap⁃
sis and biological evaluation of new ganglioside GM3 ana⁃
paB,AP ⁃ 1,and MAPKs signaling[J]. J Cell Biochem,
logues as potential agents for cancer therapy[J]. Eur J
2018,119(1):1173-1182
Med Chem,2020,189:112065
[24] LOMBARDO E,VAN ROOMEN C P,VAN PUIJVELDE
[32] OHMI Y,KAMBE M,OHKAWA Y,et al. Differential
G H,et al. Correction of liver steatosis by a hydrophobic
roles of gangliosides in malignant properties of melanomas
iminosugar modulating glycosphingolipids metabolism
[J]. PLoS One,2018,13(11):e0206881
[J]. PLoS One,2012,7(10):e38520
[33] MIYAGI T,TAKAHASHI K,YAMAMOTO K,et al. Bio⁃
[25] LOFT A,ALFARO A J,SCHMIDT S F,et al. Liver⁃fibro⁃
logical and pathological roles of ganglioside sialidases
sis ⁃ activated transcriptional networks govern hepatocyte
[J]. Prog Mol Biol Transl,2018,156:121-150
reprogramming and intra⁃hepatic communication[J]. Cell
Metab,2021,33(8):1685-1700 e9 [34] NAGAFUKU M,SATO T,SATO S,et al. Control of ho⁃
[26] LEE S M,PUSEC C M,NORRIS G H,et al. Hepatocyte⁃ meostatic and pathogenic balance in adipose tissue by
specific loss of PPARgamma protects mice from NASH ganglioside GM3[J]. Glycobiology,2015,25(3):303-
and increases the therapeutic effects of rosiglitazone in 318
the liver[J]. Cell Mol Gastroenterol Hepatol,2021,11 [收稿日期] 2021-11-03
(5):1291-1311 (本文编辑:唐 震)