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第43卷第10期        张芙蓉,苟黎明,李 妍,等. 利用CRISPER/Cas9技术构建肝脏特异性敲入Lcat基因小鼠[J].
                 2023年10月                    南京医科大学学报(自然科学版),2023,43(10):1366-1371                      ·1371 ·


                    axis contribute to hepatic osteodystrophy disease progre⁃  atherosclerotic vascular burden in a patient with familial
                    ssion[J]. Cell Metab,2022,34(3):441-457            lecithin ⁃ cholesterol acyltransferase(LCAT) deficiency
               [17] MALI P,ESVELT K M,CHURCH G M. Cas9 as a versa⁃    [J].Nephrol Dial Transplant,2008,23(3):1074
                    tile tool for engineering biology[J]. Nat Methods,2013,  [22] GEBHARD C,RHAINDS D,HE G,et al. Elevated level
                    10(10):957-963                                     of lecithin:cholesterol acyltransferase(LCAT)is associat⁃
               [18] DEVARAJU N,RAJENDIRAN V,RAVI N S,et al. Ge⁃        ed with reduced coronary atheroma burden[J]. Athero⁃
                    nome engineering of hematopoietic stem cells using CRIS⁃  sclerosis,2018,276:131-139
                    PR/Cas9 system[J]. Methods Mol Biol,2022,2429:  [23] JANAC J,ZELJKOVIC A,JELIC ⁃ IVANOVIC Z,et al.
                    307-331                                            The association between lecithin⁃cholesterol acyltransfer⁃
               [19] LYU C C,SHEN J,WANG R,et al. Targeted genome       ase activity and fatty liver index[J]. Ann Clin Biochem,
                    engineering in human induced pluripotent stem cells  2019,56(5):583-592
                    from patients with hemophilia B using the CRISPR⁃Cas9  [24] FURBEE J W,PARKS J S. Transgenic overexpression of
                    system[J]. Stem Cell Res Ther,2018,9(1):92         human lecithin:cholesterol acyltransferase(LCAT) in
               [20] VIKTÓRIA H,BALÁZS G. Genome engineering using      mice does not increase aortic cholesterol deposition[J].
                     the CRISPR⁃Cas9 system and applications in cancer re⁃  Atherosclerosis,2002,165(1):89-100
                     search[J]. Magyar Onkologia,2018,62(2):119-127                         [收稿日期] 2023-01-28
               [21] SCARPIONI R,PATIES C,BERGONZI G. Dramatic                                   (责任编辑:蒋      莉)

































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