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第43卷第6期                毋柯蓉,郭 兴. Drp1缺失通过ABCB10激活线粒体未折叠蛋白反应[J].
                  2023年6月                     南京医科大学学报(自然科学版),2023,43(6):772-779                        ·779 ·


                    Commun,2022,13(1):2340                       [19] FU Z X,LIU F,LIU C Y,et al. Mutant huntingtin inhibits
               [7] NISHIKAWA K,TAKEGAMI H,SESAKI H. Opa1⁃medi⁃         the mitochondrial unfolded protein response by impairing
                    ated mitochondrial dynamics is important for osteoclast  ABCB10 mRNA stability[J]. Biochim Biophys Acta Mol
                    differentiation[J/OL]. MicroPubl Biol,2022[2022 ⁃ 10 ⁃  Basis Dis,2019,1865(6):1428-1435
                    20]. DOI:10.17912/micropub.biology.000650    [20] SHARMA M,RAMIREZ J U N,RIVERA O,et al. Rhes,
               [8] GIACOMELLO M,PYAKUREL A,GLYTSOU C,et al.            a striatal ⁃ enriched protein,promotes mitophagy via Nix
                    The cell biology of mitochondrial membrane dynamics  [J]. Proc Natl Acad Sci U S A,2019,116(47):23760-
                    [J]. Nat Rev Mol Cell Biol,2020,21(4):204⁃224      23771
               [9] HAILESELASSIE B,MUKHERJEE R,JOSHI A U,et al.  [21] KARBOWSKI M,OSHIMA Y,VERHOEVEN N. Mito⁃
                    Drp1/Fis1 interaction mediates mitochondrial dysfunction  chondrial proteotoxicity:implications and ubiquitin ⁃ de⁃
                    in septic cardiomyopathy[J]. J Mol Cell Cardiol,2019,  pendent quality control mechanisms[J]. Cell Mol Life
                    130:160-169                                        Sci,2022,79(11):574
               [10] TATJANA K,TIMO R,JULIUS W,et al. Distinct fission  [22] DE I,DOGRA N,SINGH S. The mitochondrial unfolded
                    signatures predict mitochondrial degradation or biogenesis  protein response:role in cellular homeostasis and disease
                    [J]. Nature,2021,593(7859):435-439                [J]. Curr Mol Med,2017,17(9):587-597
               [11] JIN J Y,WEI X X,ZHI X L,et al. Drp1⁃dependent mito⁃  [23] TOMER S,HAYNES COLE M. The mitochondrial UPR:
                    chondrial fission in cardiovascular disease[J]. Acta Pra⁃  mechanisms,physiological functions and implications in
                    macol Sin,2021(5):655-664                          ageing[J]. Nat Rev Mol Cell Biol,2018,19(2):109-120
               [12] ZHAO Y,SUN X,HU D,et al. ATAD3A oligomerization  [24] KHANAM H,ALI A,ASIF M,et al. Neurodegenerative
                    causes neurodegeneration by coupling mitochondrial frag⁃  diseases linked to misfolded proteins and their therapeu⁃
                    mentation and bioenergetics defects[J]. Nat Commun,  tic approaches:a review[J]. Eur J Med Chem,2016,124:
                    2019,10(1):1371                                    1121-1141
               [13]VAILLANT⁃BEUCHOT L,MARY A,PARDOSSIP P,et      [25] LIU C,FU Z,WU S,et al. Mitochondrial HSF1 triggers
                    al. Accumulation ofamyloid precursor protein C⁃terminal  mitochondrial dysfunction and neurodegeneration in Hun⁃
                    fragments triggers mitochondrial structure,function,and  tington’s disease[J]. EMBO Mol Med,2022,14(7):
                    mitophagy defects in Alzheimer’s disease models and hu⁃  e15851
                    man brains[J]. Acta Neuropathol,2020,141(1):1-27  [26] JOSÉ P M,DINA I,VASILIKI P,et al. Loss of function of
               [14] BOLAND B,YU W H,CORTI O,et al. Promoting the       the mitochondrial peptidase PITRM1 induces proteotoxic
                    clearance of neurotoxic proteins in neurodegenerative dis⁃  stress and Alzheimer’s disease⁃like pathology in human
                    orders of ageing[J]. Nat Rev Drug Discov,2018,17(9):  cerebral organoids[J]. Mol Psychiatry,2020,26(10):
                    660-688                                            5733-5750
               [15] LIU W,SU C,QI Y,et al. Brain⁃targeted heptapeptide⁃  [27] GUO B,HUANG Y,GAO Q,et al. Stabilization of micro⁃
                    loaded exosomes attenuated ischemia ⁃ reperfusion injury  tubules improves cognitive functions and axonal transport
                    by promoting the transfer of healthy mitochondria from as⁃  of mitochondria in Alzheimer’s disease model mice[J].
                    trocytes to neurons[J]. J Nanobiotechnology,2022,20  Neurobiol Aging,2020,96:223-232
                    (1):242                                      [28] HARLAND M,TORRES S,LIU J,et al. Neuronal mito⁃
               [16] AISHWARYA R,ALAM S,ABDULLAH C S,et al. Pleio⁃      chondria modulation of LPS ⁃ induced neuroinflammation
                    tropic effects of mdivi⁃1 in altering mitochondrial dyna⁃  [J]. J Neurosci,2020,40(8):1756-1765
                    mics,respiration,and autophagy in cardiomyocytes[J].  [29] JOSHI AMIT U,MINHAS P S,LIDDELOW S A,et al.
                    Redox Biol,2020,36:101660                          Fragmented mitochondria released from microglia trigger
               [17] WANG W Z,YIN J,MA X P,et al. Inhibition of mitochon⁃  A1 astrocytic response and propagate inflammatory neuro⁃
                    drial fragmentation protects against Alzheimer’s disease  degeneration[J]. Nat Neurosci,2019,22(10):1635-1648
                    in rodent model[J]. Hum Mol Genet,2017,26(21):  [30] MENZIESUDERAM J M,JIGAR M,HONGYAUN X,et
                    4118-4131                                          al. Granulocyte⁃colony stimulating factor gene therapy as
               [18] GUO X,DISATNIK M H,MONBUREAU M,et al. Inhibi⁃      a novel therapeutics for stroke in a mouse model[J]. J
                    tion of mitochondrial fragmentation diminishes Hunting⁃  Biomed Sci,2020,27(1):99
                    ton’s disease⁃associated neurodegeneration[J]. J Clin                   [收稿日期] 2022-11-19
                    Investig,2013,123(12):5371-5388                                             (本文编辑:陈汐敏)
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