Page 107 - 南京医科大学自然版
P. 107
第44卷第5期 李盈盈,冯黎黎,韩 峰. 胶质母细胞瘤对替莫唑胺耐药机制的研究进展[J].
2024年5月 南京医科大学学报(自然科学版),2024,44(5):688-697 ·695 ·
paired primary and recurrent glioblastomas[J]. Int J Can⁃ [28]TOMAR V S,PATIL V,SOMASUNDARAM K. Temozolo⁃
cer,2011,129(3):659-670 mide induces activation of Wnt/β⁃catenin signaling in gli⁃
[16]ZHANG T X,CHAI J,CHI L Y. Induction of XLF and oma cells via PI3K/Akt pathway:implications in glioma
53BP1 expression is associated with temozolomide resis⁃ therapy[J]. Cell Biol Toxicol,2020,36(3):273-278
tance in glioblastoma cells[J]. Onco Targets Ther,2019, [29]YUN E J,KIM S,HSIEH J T,et al. Wnt/β⁃catenin signal⁃
12:10139-10151 ing pathway induces autophagy⁃mediated temozolomide⁃
[17]KANG Y J,BALTER B,CSIZMADIA E,et al. Contribu⁃ resistance in human glioblastoma[J]. Cell Death Dis,
tion of classical end⁃joining to PTEN inactivation in p53⁃ 2020,11(9):771
mediated glioblastoma formation and drug ⁃ resistant sur⁃ [30]LIU T,HU J,HAN B,et al. A positive feedback loop
vival[J]. Nat Commun,2017,8:14013 of lncRNA⁃RMRP/ZNRF3 axis and Wnt/β⁃catenin signal⁃
[18]YANG B,FU X Q,HAO J L,et al. PAXX participates in ing regulates the progression and temozolomide resistance
base excision repair via interacting with pol β and contri⁃ in glioma[J]. Cell Death Dis,2021,12(11):952
butes to TMZ resistance in glioma cells[J]. J Mol Neuro⁃ [31]LIU B Y,ZHOU J,WANG C Y,et al. LncRNA SOX2OT
sci,2018,66(2):214-221 promotes temozolomide resistance by elevating SOX2
[19]DONG W,LI L L,TENG X P,et al. End processing factor expression via ALKBH5 ⁃ mediated epigenetic regulation
APLF promotes NHEJ efficiency and contributes to TMZ⁃ in glioblastoma[J]. Cell Death Dis,2020,11(5):384
and ionizing radiation⁃resistance in glioblastoma cells[J]. [32]MENG X Q,ZHAO Y,HAN B,et al. Dual functionalized
Onco Targets Ther,2020,13:10593-10605 brain⁃targeting nanoinhibitors restrain temozolomide⁃re⁃
[20]CHAI K M,WANG C Y,LIAW H J,et al. Downregulation sistant glioma via attenuating EGFR and MET signaling
of BRCA1⁃BRCA2⁃containing complex subunit 3 sensitizes pathways[J]. Nat Commun,2020,11(1):594
glioma cells to temozolomide[J]. Oncotarget,2014,5 [33]GOODWIN C R,RATH P,OYINLADE O,et al. Crizo⁃
+
(21):10901-10915 tinib and erlotinib inhibits growth of c⁃Met /EGFRvⅢ +
[21]PATTIES I,KALLENDRUSCH S,BÖHME L,et al. The primary human glioblastoma xenografts[J]. Clin Neurol
Chk1 inhibitor SAR⁃020106 sensitizes human glioblasto⁃ Neurosurg,2018,171:26-33
ma cells to irradiation,to temozolomide,and to decitabine [34]HUANG W H,ZHONG Z,LUO C,et al. The miR⁃26a/
treatment[J]. J Exp Clin Cancer Res,2019,38(1):420 AP⁃2α/Nanog signaling axis mediates stem cell self⁃re⁃
[22]LI H,CHEN L,LI J J,et al. MiR⁃519a enhances chemo⁃ newal and temozolomide resistance in glioma[J]. Ther⁃
sensitivity and promotes autophagy in glioblastoma by tar⁃ anostics,2019,9(19):5497-5516
geting STAT3/Bcl2 signaling pathway[J]. J Hematol On⁃ [35]ZHAO C G,YU H H,FAN X Q,et al. GSK3β palmi⁃
col,2018,11(1):70 toylation mediated by ZDHHC4 promotes tumorigenicity
[23]GE X,PAN M H,WANG L,et al. Hypoxia⁃mediated mito⁃ of glioblastoma stem cells in temozolomide⁃resistant glio⁃
chondria apoptosis inhibition induces temozolomide treat⁃ blastoma through the EZH2⁃STAT3 axis[J]. Oncogene⁃
ment resistance through miR⁃ 26a/Bad/Bax axis[J]. Cell sis,2022,11(1):28
Death Dis,2018,9(11):1128 [36]CHIANG I T,LIU Y C,LIU H S,et al. Regorafenib reverses
[24]CANCER GENOME ATLAS RESEARCH NETWORK. temozolomide ⁃ induced CXCL12/CXCR4 signaling and
Comprehensive genomic characterization defines human triggers apoptosis mechanism in glioblastoma[J]. Neuro⁃
glioblastoma genes and core pathways[J]. Nature,2008, therapeutics,2022,19(2):616-634
455(7216):1061-1068 [37]LI H Y,FENG Y H,LIN C L,et al. Mitochondrial mecha⁃
[25]SINGH N,MINER A,HENNIS L,et al. Mechanisms of nisms in temozolomide resistance:unraveling the complex
temozolomide resistance in glioblastoma ⁃ a comprehen⁃ interplay and therapeutic strategies in glioblastoma[J].
sive review[J]. Cancer Drug Resist,2021,4(1):17-43 Mitochondrion,2023,75:101836
[26]XIE Y,ZHONG D W. AEG⁃1 is associated with hypoxia⁃ [38]GARCIA J H,JAIN S,AGHI M K. Metabolic drivers of in⁃
induced hepatocellular carcinoma chemoresistance via vasion in glioblastoma[J]. Front Cell Dev Biol,2021,9:
regulating PI3K/AKT/HIF⁃ 1 alpha/MDR⁃ 1 pathway[J]. 683276
EXCLI J,2016,15:745-757 [39]TSAI Y T,LO W L,CHEN P Y,et al. Reprogramming of
[27]PRASAD G,SOTTERO T,YANG X D,et al. Inhibition of arachidonate metabolism confers temozolomide resistance
PI3K/mTOR pathways in glioblastoma and implications to glioblastoma through enhancing mitochondrial activity
for combination therapy with temozolomide[J]. Neuro in fatty acid oxidation[J]. J Biomed Sci,2022,29(1):21
Oncol,2011,13(4):384-392 [40]CHENG S Y,CHEN N F,WEN Z H,et al. Glutathione S⁃