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第44卷第9期 许程晨,张梦澄,冯俊成,等. 股直肌剪切波弹性成像对胸腔镜术后肺部并发症的预测价值[J].
2024年9月 南京医科大学学报(自然科学版),2024,44(9):1268-1273,1304 ·1273 ·
子⁃α、白介素⁃6、白介素⁃8和C⁃反应蛋白等炎性介质 pulmonary function:republication of systematic review
与患者的骨骼肌刚度降低相关。炎性介质的释放 and proposals by guideline committee of the Japanese as⁃
导致肌肉释放的氨基酸减少,这可能影响肺部的免 sociation for chest surgery 2014[J]. Gen Thorac Cardio⁃
疫功能和组织修复能力,增加了术后肺部感染等并 vasc Surg,2015,63(1):14-21
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发症的风险。然而,本研究发现股直肌RFthick和RFcsa
liability of quantitative point shear⁃wave ultrasound elas⁃
与术后 PPC 之间没有显著相关性,而股直肌 CSmeans
tography on vastus medialis muscle and quadriceps and
与术后PPC 之间存在显著相关性,这再次表明通过
patellar tendons[J]. Med Ultrason,2019,21(1):50-55
测量弹性数值能更早地显示出全身肌肉质量的变 [6] 刘博姬,徐辉雄. 剪切波弹性成像在肌肉、肌腱、周围神
化 [22] 。③由于分组中年龄分布广泛,预测结果可能 经病变生物力学定量评估中的应用进展[J]. 肿瘤影像
存在偏倚。为此,采用多因素Logistic回归模型进行 学,2022,31(1):11-15
校正,并计算出联合诊断公式,以评估分析联合预 [7] DENG M,ZHOU X,LI Y,et al. Ultrasonic elastography of
测 PPC 的价值。分析发现:年龄与 CSmean联合诊断 the rectus femoris,a potential tool to predict sarcopenia in
后,AUC达0.714(95%CI:0.647~0.781),显著高于单 patients with chronic obstructive pulmonary disease[J].
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个指标的预测效能。因此,本研究认为股直肌CSmean
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联合年龄对胸腔镜手术患者术后 PPC 的发生情况
et al. Effects of inspiratory muscle training on respiratory
具有较好的临床预测价值。通过超声检查评估股
muscle electromyography and dyspnea during exercise in
直肌状态,从而识别 PPC 高危患者,并以此为导向 healthy men[J]. J Appl Physiol(1985),2017,122(5):
优化围术期 PPC的预防策略,对于术前评估为重度 1267-1275
肌肉功能减退的患者,可采用阻抗运动和平衡运动 [9] YI J,SHIN Y,HAHN S,et al. Deep learning based sarco⁃
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等预康复策略,以减少PPC的发生 。 penia prediction from shear⁃wave ultrasonographic elas⁃
本研究为单中心观察性研究,可能存在混杂偏 tography and gray scale ultrasonography of rectus femoris
倚,且样本量较小及缺乏外部验证,存在一定的局限 muscle[J]. Sci Rep,2022,12(1):3596
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性。另本研究未将超声测量结果和CT扫描评估或力
operative pulmonary complications updating[J]. Ann Fr
量强度进行比较,在未来的研究中,计划持续增加样
Anesth Reanim,2014,33(7⁃8):480-483
本量,结合其他影像学资料,进一步验证改良模型的
[11]宋田皓,王丽君,李彭依,等. 不同水平呼气末正压通气
预测效力,并通过多中心队列研究进行外部验证。 联合60%吸入氧浓度对单肺通气患者氧合及术后肺部
综上,基于 SWE 对术前股直肌状态的定量评 并发症的影响[J]. 南京医科大学学报(自然科学版),
估,结合年龄指标,有利于提高胸腔镜手术患者术 2021,41(4):528-533
前PPC 风险评估的客观性及可靠性,为临床决策提 [12]UHLIG C,NETO A S,VANDER WOUDE M,et al. Intra⁃
供有效参考。 operative mechanical ventilation practice in thoracic sur⁃
gery patients and its association with postoperative pulmo⁃
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