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第44卷第9期        许程晨,张梦澄,冯俊成,等. 股直肌剪切波弹性成像对胸腔镜术后肺部并发症的预测价值[J].
                  2024年9月                  南京医科大学学报(自然科学版),2024,44(9):1268-1273,1304                    ·1273 ·


                子⁃α、白介素⁃6、白介素⁃8和C⁃反应蛋白等炎性介质                            pulmonary function:republication of systematic review
                与患者的骨骼肌刚度降低相关。炎性介质的释放                                  and proposals by guideline committee of the Japanese as⁃
                导致肌肉释放的氨基酸减少,这可能影响肺部的免                                 sociation for chest surgery 2014[J]. Gen Thorac Cardio⁃
                疫功能和组织修复能力,增加了术后肺部感染等并                                 vasc Surg,2015,63(1):14-21
                                                                 [5] ZARDI E M,FRANCESCHRTTI E,GIORGI C,et al. Re⁃
                发症的风险。然而,本研究发现股直肌RFthick和RFcsa
                                                                       liability of quantitative point shear⁃wave ultrasound elas⁃
                与术后 PPC 之间没有显著相关性,而股直肌 CSmeans
                                                                       tography on vastus medialis muscle and quadriceps and
                与术后PPC 之间存在显著相关性,这再次表明通过
                                                                       patellar tendons[J]. Med Ultrason,2019,21(1):50-55
                测量弹性数值能更早地显示出全身肌肉质量的变                            [6] 刘博姬,徐辉雄. 剪切波弹性成像在肌肉、肌腱、周围神
                化 [22] 。③由于分组中年龄分布广泛,预测结果可能                            经病变生物力学定量评估中的应用进展[J]. 肿瘤影像
                存在偏倚。为此,采用多因素Logistic回归模型进行                            学,2022,31(1):11-15
                校正,并计算出联合诊断公式,以评估分析联合预                           [7] DENG M,ZHOU X,LI Y,et al. Ultrasonic elastography of
                测 PPC 的价值。分析发现:年龄与 CSmean联合诊断                          the rectus femoris,a potential tool to predict sarcopenia in
                后,AUC达0.714(95%CI:0.647~0.781),显著高于单                   patients with chronic obstructive pulmonary disease[J].
                                                                       Front Physiol,2022,12:783421.
                个指标的预测效能。因此,本研究认为股直肌CSmean
                                                                 [8] RAMSOOK A H,MOLGAT⁃SEON Y,SCHAEFFER M R,
                联合年龄对胸腔镜手术患者术后 PPC 的发生情况
                                                                       et al. Effects of inspiratory muscle training on respiratory
                具有较好的临床预测价值。通过超声检查评估股
                                                                       muscle electromyography and dyspnea during exercise in
                直肌状态,从而识别 PPC 高危患者,并以此为导向                              healthy men[J]. J Appl Physiol(1985),2017,122(5):
                优化围术期 PPC的预防策略,对于术前评估为重度                               1267-1275
                肌肉功能减退的患者,可采用阻抗运动和平衡运动                           [9] YI J,SHIN Y,HAHN S,et al. Deep learning based sarco⁃
                                              [23]
                等预康复策略,以减少PPC的发生 。                                     penia prediction from shear⁃wave ultrasonographic elas⁃
                    本研究为单中心观察性研究,可能存在混杂偏                               tography and gray scale ultrasonography of rectus femoris
                倚,且样本量较小及缺乏外部验证,存在一定的局限                                muscle[J]. Sci Rep,2022,12(1):3596
                                                                 [10]LANGERON O,CARREIRA S,lE SACGÉ F,et al. Post⁃
                性。另本研究未将超声测量结果和CT扫描评估或力
                                                                       operative pulmonary complications updating[J]. Ann Fr
                量强度进行比较,在未来的研究中,计划持续增加样
                                                                       Anesth Reanim,2014,33(7⁃8):480-483
                本量,结合其他影像学资料,进一步验证改良模型的
                                                                 [11]宋田皓,王丽君,李彭依,等. 不同水平呼气末正压通气
                预测效力,并通过多中心队列研究进行外部验证。                                 联合60%吸入氧浓度对单肺通气患者氧合及术后肺部
                    综上,基于 SWE 对术前股直肌状态的定量评                             并发症的影响[J]. 南京医科大学学报(自然科学版),
                估,结合年龄指标,有利于提高胸腔镜手术患者术                                 2021,41(4):528-533
                前PPC 风险评估的客观性及可靠性,为临床决策提                         [12]UHLIG C,NETO A S,VANDER WOUDE M,et al. Intra⁃
                供有效参考。                                                 operative mechanical ventilation practice in thoracic sur⁃
                                                                       gery patients and its association with postoperative pulmo⁃
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                    assessment of lung resection for lung cancer according to                   (下转第1304页)
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