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表3 顺产产妇发生与未发生产后出血组特征比较
Table 3 Characteristics comparison between women with and without postpartum hemorrhage(natural birth)
Characteristics Without postpartum hemorrhage(n=81) With postpartum hemorrhage(n=20) P
Age(years,x ± s) 31.14 ± 4.16 33.15 ± 5.49 0.073
Pregnancy times[n,M(P25,P75)] 2.00(1.00,3.00)0 2.00(2.00,3.50)00 0.057
Delivery history[n(%)] 33(40.7)0000 10(50.0)00000 0.619
Abortion history[n(%)] 34(42.0)0000 14(70.0)00000 0.046
Late pregnancy BMI(kg/m ,x ± s) 25.71 ± 2.89 26.10 ± 3.06 0.744
2
Assisted reproduction[n(%)] 4(4.9)0000 3(15.0)0000 0.273
Fetal position[n(%)] —
Cephalic presentation 81(100.0)00 20(100.0)000
Breech presentation 0 0
PT[s,M(P25,P75)] 10.80(10.30,11.30) 11.25(10.62,11.57)0 0.292
PT⁃INR[s,M(P25,P75)] 0.93(0.89,0.98)0 0.98(0.92,1.01)00 0.245
APTT[s,M(P25,P75)] 26.25(25.02,28.50) 25.25(24.05,27.00)0 0.182
FIB[g/L,M(P25,P75)] 3.91(3.14,4.93)0 4.27(3.55,4.59)00 0.372
TT[s,M(P25,P75)] 16.40(15.80,17.52) 16.05(15.70,16.40)0 0.195
D⁃dimer[mg/L,M(P25,P75)] 1.89(1.18,2.79)0 4.47(1.89,5.32)00 0.004
HbA1c[%,M(P25,P75)] 5.10(4.93,5.30)0 5.00(4.70,5.13)00 0.134
OGTT[mmol/L,M(P25,P75)]
Fasting 4.75(4.36,5.25)0 4.45(4.23,4.71)00 0.123
1 h 9.92(9.04,10.65) 10.27(9.30,10.60)00 0.502
2 h 8.35(7.58,8.95)0 8.94(8.15,9.12)0 0.075
PLT[×10 /L,M(P25,P75)] 107.00(92.00,143.00) 98.50(89.25,105.75) 0.034
9
ALB[g/L,M(P25,P75)] 35.70(33.90,38.12) 39.90(39.40,43.90)0 0.076
HSCRP[mg/L,M(P25,P75)] 1.17(0.50,4.46)0 7.50(3.97,12.85)0 0.034
PCT[%,M(P25,P75)] 0.13(0.11,0.15)0 0.12(0.11,0.14)00 0.304
HGB[g/L,M(P25,P75)] 122.0(115.0,129.0) 121.5(111.0,127.5)0 0.511
Pregnant women outcomes
Delivery time(weeks,x ± s) 38.73 ± 1.90 39.15 ± 1.60 0.363
Preterm delivery[n(%)] 6(7.4)0000 1(5.0)00000 1.000
Premature rupture of membranes[n(%)] 19(23.5)0000 4(20.0)0000 0.974
Intrapartum hemorrhage[mL,M(P25,P75)] 200.0(200.0,252.5) 450.0(337.5,500.0)0 <0.001
Postpartum hemorrhage[mL,M(P25,P75)] 330.0(290.0,419.5) 600.0(540.0,722.5)0 <0.001
Newborn outcomes
Weight(g,x ± s) 3 369.14 ± 481.12 3 482.50 ± 390.77 0.331
Female[n(%)] 31(38.3)0000 12(60.0)00000 0.132
5 min Apgar score[n(%)] 0.852
9 1(1.2)0000 1(5.0)00000
10 80(98.8)0000 19(95.0)00000
Neonatal distress[n(%)] 1(1.2)0000 0 1.000
NICU[n(%)] 16(19.8)0000 3(15.0)0000 0.867
要不良结局之一。研究表明,GDM可通过影响子宫 析显示产前 D⁃二聚体及 PLT 水平是影响 GDM 合并
收缩、产程、胎儿体重、胎盘功能等途径,从而增加 TCP产妇产后出血风险的独立因素。这一结果与既
产妇产后出血的风险 [11] 。与未发生产后出血的产 往研究报道相一致。如张颖等 [12] 研究发现,产后出
妇相比,发生产后出血产妇产前PT、PT⁃INR、D⁃二聚 血组产妇产前D⁃二聚体显著高于健康产妇,并且产
体水平显著增高,而 PLT 显著下降。多因素回归分 前D⁃二聚体水平可预测产后出血风险。同样,王斐

