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第45卷第10期           徐丽琴,许叶涛,张 敏. 妊娠期糖尿病合并血小板减少女性不良妊娠结局的影响因素
                 2025年10月                 研究[J]. 南京医科大学学报(自然科学版),2025,45(10):1443-1454                  ·1447 ·


                                               表2 产后出血组与无产后出血组特征比较
                            Table 2 Characteristics comparison between women with and without postpartum hemorrhage
                           Characteristics       Without postpartum hemorrhage(n=203) With postpartum hemorrhage(n=30)  P
                Age(years,x ± s)                            31.84 ± 4.30                32.67 ± 5.05       0.339
                Pregnancy times[n,M(P25,P75)]            2.00(1.00,3.00)0             2.00(2.00,3.50)0     0.050
                Delivery history[n(%)]                     85(41.9)0000                17(56.7)0000        0.184
                Abortion history[n(%)]                    100(49.3)00000               20(66.7)0000        0.113
                Comorbidity[n(%)]                          58(28.6)0000                13(43.3)0000        0.154
                Assisted reproduction[n(%)]                19(9.4)00000                 4(13.3)000         0.724
                Late pregnancy BMI(kg/m ,x ± s)             26.72 ± 3.00                26.76 ± 3.03       0.967
                                   2
                Fetal position[n(%)]                                                                       0.254
                  Cephalic presentation                   188(92.6)00000               30(100)000 0
                  Breech presentation                      15(7.4)00000                     0
                PT[s,M(P25,P75)]                        10.85(10.30,11.38)           11.30(10.70,11.62)    0.027
                PT⁃INR[s,M(P25,P75)]                     0.94(0.90,0.99)0             0.98(0.93,1.01)0     0.023
                APTT[s,M(P25,P75)]                      26.10(24.30,27.87)           26.50(24.20,29.25)    0.555
                FIB[g/L,M(P25,P75)]                      3.89(3.12,4.65)0             4.00(3.43,4.41)0     0.990
                TT[s,M(P25,P75)]                        16.40(15.70,17.30)           16.22(15.42,16.85)    0.642
                D⁃dimer[mg/L,M(P25,P75)]                 2.02(1.27,3.21)0             4.18(2.23,5.51)0     <0.001
                HbA1c[%,M(P25,P75)]                      5.11(4.90,5.40)0             5.00(4.74,5.25)0     0.240
                OGTT[mmol/L,M(P25,P75)]
                  Fasting                                 4.86(4.47,5.24)0            4.64(4.36,5.09)0     0.122
                  1 h                                   10.20(9.22,10.91)0            9.82(9.13,10.54)     0.279
                  2 h                                    8.54(7.59,9.20)0             8.80(8.12,9.37)0     0.463
                PLT[×10 /L,M(P25,P75)]                  107.0(88.0,134.5)0           097.0(80.2,105.0)0    0.012
                       9
                ALB[g/L,M(P25,P75)]                     35.00(32.55,37.32)           39.65(35.43,42.90)    0.073
                HSCRP[mg/L,M(P25,P75)]                   2.06(0.99,5.00)0             5.00(1.60,9.38)0     0.167
                PCT[%,M(P25,P75)]                        0.13(0.11,0.15)0             0.11(0.10,0.14)0     0.130
                HGB[g/L,M(P25,P75)]                     122.0(114.0,132.0)           120.5(107.3,128.5)    0.305
                Pregnant women outcomes
                  Delivery time(weeks,x ± s)                38.20 ± 2.12                38.83 ± 1.51       0.117
                  Cesarean[n(%)]                          122(60.1)00000               10(33.3)0           0.010
                  Preterm delivery[n(%)]                   25(12.3)0000                 1(3.3)0 00         0.251
                  Premature rupture of membranes[n(%)]     33(16.3)0000                 5(16.7)00          1.000
                  Intrapartum hemorrhage[mL,M(P25,P75)]  300.0(250.0,400.0)          500.0(412.5,800.0)    <0.001
                  Postpartum hemorrhage[mL,M(P25,P75)]  450.0(352.5,563.8)          0 722.5(544.5,1 092.5)  <0.001
                Newborn outcomes
                  Weight(g,x ± s)                        3 352.36 ± 639.81            3 514.87 ± 486.57    0.183
                  Female[n(%)]                             92(45.3)0000                16(53.3)0000        0.532
                5 min Apgar score[n(%)]                                                                    1.000
                  7                                         2(1.0)0000                      0
                  8-10                                    201(99.0)00000               30(100)0000
                Neonatal distress[n(%)]                    12(5.9)00000                     0              0.355
                NICU[n(%)]                                 39(19.2)0000                 4(13.3)000         0.601


                3.8‰。然而,GDM 合并 TCP 产妇产后出血、早产、                     D⁃二聚体、血小板及孕晚期BMI是主要不良母婴结
                新生儿体重异常等母婴不良妊娠结局发生率较                              局的影响因素。
                高。多因素回归分析表明,空腹血糖、其他合并症、                               本研究发现,产后出血是GDM合并TCP产妇主
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