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               ·358 ·                            南 京    医 科 大 学 学         报                        2025年3月


              得良好预后,同时具有较好的安全性,但无法完全                            [6] DEGUCHI I,TAKAHASHI S. Pathophysiology and opti⁃
              阻止END,需要加强对黏膜出血及卒中相关肺炎等                                mal treatment of intracranial branch atheromatous dis⁃
              并发症的预防,为临床诊治提供参考。此外,本研                                 ease[J]. J Atheroscler Thromb,2023,30(7):701-709
              究存在一定不足:本研究为单中心回顾性研究,样                            [7] PETRONE L,NANNONI S,DEL BENE A,et al. Branch
              本量较小,存在偏倚的可能,后期需要扩大样本及                                 atheromatous disease:a clinically meaningful,yet unprov⁃
                                                                     en concept[J]. Cerebrovasc Dis,2016,41(1/2):87-95
              多中心研究进一步证实;其次,本研究未与≥80 岁
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              BAD非溶栓患者比较,静脉溶栓能否减少高龄BAD
                                                                     stroke related to intracranial branch atheromatous disease
              患者的END发生风险,以及高龄患者BAD患者发生
                                                                     and comparison with large and small artery diseases[J]. J
              END的其他危险因素仍有待进一步研究。                                    Neurol Sci,2011,303(1/2):80-84
                  利益冲突声明:                                       [9] LI S D,WANG L H,LIU B,et al. Clinical and prognostic
                  所有作者均声明不存在利益冲突。                                    characteristics of acute BAD⁃related stroke:a multicenter
                  Conflict of Interests:                             MRI⁃based prospective study[J]. Stroke,2024,55(10):
                  The authors have no conflict of interests to declare.
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                  作者贡献声明:                                       [10]WU X B,LIU Y,NIE C,et al. Efficacy and safety of intra⁃
                  高甜文负责论文设计、数据收集、数据分析、论文撰写、
                                                                     venous thrombolysis on acute branch atheromatous dis⁃
              经费支持;马志负责数据收集、数据分析;曹辉负责研究指                             ease:a retrospective case⁃control study[J]. Front Neurol,
              导、论文修改;邱峰负责论文设计、研究指导、论文修改。
                                                                     2020,11:581
                  Author’s Contributions:                       [11]付胜奇,朱利利,李浩然,等. 替奈普酶静脉溶栓治疗穿
                  GAO Tianwen was responsible for study design,data acqui⁃  支动脉粥样硬化病的效果观察[J]. 中华医学杂志,
              sition,data analysis,manuscript writing,and financial support;
                                                                     2023,103(23):1753-1758
              MA Zhi contributed to data acquisition and data analysis;CAO
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              Hui was involved in supervision and critical revision of the man⁃
                                                                     thrombolysis with tenecteplase in treating the branch ath⁃
              uscript;QIU Feng handled study design,supervision,and criti⁃
                                                                     eromatous disease[J]. National Medical Journal of China,
              cal revision of the manuscript.
                                                                     2023,103(23):1753-1758
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