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表2 DFS的单变量和多变量 Cox 分析
Table 2 Univariate and multivariable Cox analyses of DFS
Univariate analysis Multivariate analysis
Variable
P HR 95% CI P HR 95% CI
Age 0.401 1.017 0.977-1.059 - - -
Sex
Female 0.550 1.292 0.558-2.996 - - -
Male 0.550 0.774 0.334-1.793 - - -
BMI 0.721 0.975 0.846-1.122 - - -
BMI group
< 25 kg/m 2 0.309 1.678 0.619-4.551 - - -
≥25 kg/m 2 0.309 0.596 0.220-1.616 - - -
SMA 0.185 0.990 0.975-1.005 - - -
SAA 0.484 1.002 0.996-1.009 - - -
VAA 0.999 1.000 0.993-1.007 - - -
LAMA 0.345 1.013 0.987-1.040 - - -
SMI 0.175 0.966 0.918-1.016 - - -
SAI 0.388 1.008 0.990-1.026 - - -
VAI 0.848 1.002 0.982-1.023 - - -
Sarcopenia
No 0.052 0.422 0.177-1.008 0.946 0.952 0.231-3.929
Yes 0.052 2.371 0.992-5.667 0.946 1.051 0.255-4.337
SAI group
Low 0.861 1.087 0.425-2.781 - - -
High 0.861 0.920 0.360-2.352 - - -
VAI group
Low 0.562 0.745 0.275-2.019 - - -
High 0.562 1.343 0.495-3.643 - - -
LAMA/SMA 0.020 1.043 1.007-1.081 - - -
Myosteatosis
No 0.061 0.312 0.092-1.054 0.048 0.237 0.057-0.985
Yes 0.061 3.207 0.948-10.840 0.048 4.217 1.015-17.522
CXI 0.049 0.988 0.975-0.999 - - -
CXI group
Low 0.035 2.497 1.067-5.847 0.108 2.247 0.838-6.025
High 0.035 0.400 0.171-0.938 0.108 0.445 0.166-1.194
FFM 0.185 0.967 0.919-1.016 - - -
Drug dose 0.081 1.136 0.984-1.312 0.450 1.083 0.880-1.333
Risk stratification
Moderate a 1.000 - - 1.000 - -
High 0.049 2.967 1.003-8.772 0.013 4.743 1.386-16.235
C⁃KIT mutations
a
Exon 11 1.000 - - 1.000 - -
Exon 9 0.040 3.188 1.055-9.633 0.040 3.464 1.057-11.351
Exon 13 0.014 6.443 1.454-28.548 0.001 15.420 2.889-82.298
Wild type 0.540 1.886 0.248-14.336 0.647 0.613 0.075-4.987
a：Reference categories.