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表3 不同条栅视力状态儿童神经发育欠佳的频数分布
Table 3 Distribution of the frequency of noncompetent neurodevelopment according to visual acuity status [n(%)]
Noncompetent neurodevelopment Total(n=1 122) Control group(n=1 028) Abnormal visual acuity(n=94) χ 2 P
Cognition 52(4.6) 47(4.6) 5(5.3) 0.005 0.941
Receptive communication 39(3.5) 35(3.4) 4(4.3) 0.019 0.891
Expressive communication 45(4.0) 41(4.0) 4(4.3) 0.001 0.999
Fine motor 116(10.3) 104(10.1) 12(12.8) 0.398 0.528
Gross motor 77(6.9) 65(6.3) 12(12.8) 4.631 0.031
表4 婴儿期条栅视力与3岁神经发育欠佳的关联
Table 4 Associations between infant visual acuity and noncompetentneurodevelopment at 3 years of age
Model 1 a Model 2 b
Outcome
RR(95% CI) P RR(95% CI) P
Cognition 1.16(0.46-2.92) 0.748 1.09(0.42-2.84) 0.853
Receptive communication 1.25(0.44-3.52) 0.673 1.25(0.43-3.64) 0.687
Expressive communication 1.07(0.38-3.01) 0.905 1.17(0.40-3.41) 0.746
Fine motor 1.26(0.69-2.29) 0.446 1.16(0.63-2.15) 0.628
Gross motor 2.02(1.09-3.74) 0.025 1.96(1.03-3.70) 0.040
a:Unadjusted for covariates. b:Adjusted for maternal age,household income,maternal education,gestational age,pre⁃pregnancy BMI,plurality,hy⁃
pertensive disorders of pregnancy,diabetes mellitus in pregnancy,sex,breastfeedingduration,age at visual acuity assessment,age at neurodevelopmen⁃
tal assessment. RR:risk ratio;CI:confidence interval.
表5 婴儿期条栅视力与3岁神经发育欠佳关联的性别分层分析
Table 5 Associations between infant visual acuity and noncompetent neurodevelopment at 3 years of agestratified by child
sex
a
Variable Control group[n/N(%)] Abnormal visual acuity[n/N(%)] Adjusted RR(95% CI)P value for heterogeneity
Cognition 0.922
Boy 37/532(7.0)0 4/42(9.5) 1.15(0.39-3.39)0
Girl 10/496(2.0)0 1/52(1.9) 1.02(0.12-8.51)0
Receptive communication 0.846
Boy 27/532(5.1)0 3/42(7.1) 1.30(0.37-4.57)0
Girl 08/496(1.6)0 1/52(1.9) 1.68(0.18-15.58)
Expressive communication 0.796
Boy 33/532(6.2)0 3/42(7.1) 1.08(0.31-3.79)0
Girl 8/496(1.6) 1/52(1.9) 1.50(0.17-13.43)
Fine motor 0.148
Boy 72/532(13.5) 10/42(23.8) 1.56(0.78-3.13)0
Girl 32/496(6.5)0 2/52(3.8) 0.48(0.11-2.02)0
Gross motor 0.443
Boy 41/532(7.7)0 08/42(19.0) 2.31(1.03-5.21)0
Girl 24/496(4.8)0 4/52(7.7) 1.37(0.47-4.01)0
a:Adjusted for maternal age,household income,maternal education,gestational age,pre⁃pregnancy BMI,plurality,hypertensive disorders of preg⁃
nancy,diabetes mellitus in pregnancy,breastfeeding duration,age at visual acuity assessment,age at neurodevelopmental assessment. RR:risk ratio;
CI:confidence interval.
表6。当分别排除双胎、早产儿、低出生体重儿及辅 儿期条栅视力异常组3岁时大运动发育欠佳的风险
助生殖受孕出生的儿童后,结果与主分析基本一 在排除双胎后增加 136%(RR=2.36,95%CI:1.21~
致。具体而言,与婴儿期条栅视力正常组相比,婴 4.58)、在排除早产儿后增加 142%(RR=2.42,95%

