Page 162 - 南京医科大学自然版
P. 162

第46卷第6期
               ·944  ·                           南 京    医 科 大 学 学         报                        2026年6月


                   breast cancer[J]. J Biol Chem,2020,295(41):14140-  obic glycolysis and overcomes chemoresistance by induc⁃
                   14152                                             ing Cdh1 ⁃ mediated Skp2 ubiquitination[J]. Am J Chin
             [52]DAS C K,PAREKH A,PARIDA P K,et al. Lactate dehy⁃    Med,2023,51(3):723-740
                   drogenase a regulates autophagy and tamoxifen resistance  [61]DONG X,LI K,WANG R,et al. Targeting Skp2 by tanshi⁃
                   in breast cancer[J]. Biochim Biophys Acta Mol Cell Res,  none IIA overcomes chemoresistance in colorectal can⁃
                   2019,1866(6):1004-1018                            cer[J]. Cell Biol Toxicol,2025,41(1):135
             [53]CHEN X,LUO R,ZHANG Y,et al. Long noncoding RNA  [62]SHEN D,DENG Z,LIU W,et al. Melatonin inhibits blad⁃
                   DIO3OS induces glycolytic ⁃ dominant metabolic repro⁃  der tumorigenesis by suppressing PPARγ/ENO1⁃mediat⁃
                   gramming to promote aromatase inhibitor resistance in  ed glycolysis[J]. Cell Death Dis,2023,14(4):246
                   breast cancer[J]. Nat Commun,2022,13(1):7160  [63]HU Y,LOU X,ZHANG K,et al. Tumor necrosis factor re⁃
             [54]CHEN Y,ZHANG J,ZHANG M,et al. Baicalein resensi⁃    ceptor 2 promotes endothelial cell⁃mediated suppression
                                                                          +
                   tizes tamoxifen⁃resistant breast cancer cells by reducing  of CD8 T cells through tuning glycolysis in chemoresis⁃
                   aerobic glycolysis and reversing mitochondrial dysfunc⁃  tance of breast cancer[J]. J Transl Med,2024,22(1):
                   tion via inhibition of hypoxia⁃inducible factor⁃1α[J]. Clin  672
                   Transl Med,2021,11(11):e577                  [64]LI X,ZHANG C,MEI Y,et al. Irinotecan alleviates che⁃
             [55]CHEN H,LI Y,LI H,et al. NBS1 lactylation is required  moresistance to anthracyclines through the inhibition of
                   for efficient DNA repair and chemotherapy resistance[J].  AARS1⁃mediated BLM lactylation and homologous recom⁃
                   Nature,2024,631(8021):663-669                     bination repair[J]. Sig Transduct Target Ther,2025,10
             [56]FENG J,DAI W,MAO Y,et al. Simvastatin re⁃sensitizes  (1):214
                   hepatocellular carcinoma cells to sorafenib by inhibiting  [65]XU Q,GAO J,ZHAO R,et al. Akkermansia muciniphila⁃
                   HIF ⁃ 1α/PPAR ⁃ γ/PKM2 ⁃ mediated glycolysis[J]. J Exp  derived pentadecanoic acid enhances oxaliplatin sensitivity
                   Clin Cancer Res,2020,39(1):24                     in gastric cancer by modulating glycolysis[J]. Pharmacol
             [57]BI L,REN Y,FENG M,et al. HDAC11 regulates glycoly⁃  Res,2024,206:107278
                   sis through the LKB1/AMPK signaling pathway to main⁃  [66]LU H,TONG W,JIANG M,et al. Mitochondria⁃targeted
                   tain hepatocellular carcinoma stemness[J]. Cancer Res,  multifunctional nanoprodrugs by inhibiting metabolic
                   2021,81(8):2015-2028                              reprogramming for combating cisplatin ⁃ resistant lung
             [58]WANG J,HUANG Q,HU X,et al. Disrupting circadian     cancer[J]. ACS Nano,2024,18(32):21156-21170
                   rhythm via the PER1⁃HK2 axis reverses trastuzumab re⁃  [67]ZHANG R,LI R,ZHANG L,et al. A dual ⁃ mechanism
                   sistance in gastric cancer[J]. Cancer Res,2022,82(8):  based nutrient partitioning nanoregulator for enhanced im⁃
                   1503-1517                                         munotherapy against anti⁃PD⁃1 resistant tumors[J]. ACS
             [59]YANG J,WANG H,LI B,et al. Inhibition of ACSS2 trig⁃  Nano,2023,17(14):13461-13473
                   gers glycolysis inhibition and nuclear translocation to acti⁃  [68]SCHWENCK J,SONANINI D,COTTON J M,et al. Ad⁃
                   vate SIRT1/ATG5/ATG2B deacetylation axis,promoting  vances in PET imaging of cancer[J]. Nat Rev Cancer,
                   autophagy and reducing malignancy and chemoresistance  2023,23(7):474-490
                   in ovarian cancer[J]. Metabolism,2025,162:156041  (收稿:2026-02-11;修回:2026-04-19;录用:2026-04-20)
             [60]GAN Y,ZHOU L,WANG R,et al. Curcumol reduces aer⁃                             (本文编辑:唐       震)
   157   158   159   160   161   162   163   164   165   166   167