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第4期 总第135期 南京医科大学学报（社会科学版）京医科大学学报（社会科学版） ·
南
2026年8月 Journal of Nanjing Medical University（Social Sciences）of Nanjing Medical University（Social Sciences） · 377
Journal

Association between cMIND diet trajectories and cognitive function in

older adults

1
1
Chen Yiyun ，Lin Yihui ，Lin Zhongyue 2
1. Department of State⁃owned Assets Management，2. School of Health，Fujian Medical University，Fuzhou 350122，China
Abstract：Cognitive impairment poses a major public health challenge in aging societies，and dietary
nutrition is considered a key modifiable target. The China⁃adapted MIND（cMIND）diet has been preliminarily
established，but longitudinal evidence supporting its association with cognitive impairment among older adults
remains limited. This study focused on Chinese older adults aged ≥65 years and used four waves of data（2008-
2018）from the Chinese Longitudinal Healthy Longevity Survey（CLHLS）to identify long⁃term trajectories of
cMIND diet adherence through latent class growth analysis and examine their relationship with cognitive
impairment. Results showed that cMIND diet adherence among older adults followed four distinct trajectories:
persistently high，stable moderate，moderate⁃declining，and persistently low. Compared with the persistently
high adherence group，the risk of cognitive impairment was 35% higher in the moderate⁃declining group，and
48% higher in the persistently low group（both P<0.05）. Advanced age，educational level below elementary
school，rural residence，lack of regular physical exercise，and depression were independent risk factors for low⁃
adherence trajectories. Maintaining long⁃term high adherence to the cMIND diet，rather than focusing solely on
one ⁃ time intake，is an important modifiable target for preventing cognitive impairment among older adults.
Community ⁃ based nutritional interventions should be initiated early and sustained over the long ⁃ term，with
particular attention to vulnerable populations，including rural residents and those with low educational levels.
Key words：cMIND diet；cognitive impairment；dietary trajectory；CLHLS；older adults