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               ·1440 ·                           南 京    医 科 大 学 学         报                        2023年10月


                   distal regulatory sites characterizes dysregulation of can⁃  NuRD subunit CHD4 regulates super⁃enhancer accessibil⁃
                   cer genes[J]. Genome Biol,2013,14(3):R21          ity in rhabdomyosarcoma and represents a general tumor
             [47] FLEISCHER T,TEKPLI X,MATHELIER A,et al. DNA        dependency[J]. Elife,2020,9:e54993
                   methylation at enhancers identifies distinct breast cancer  [60] YI M,TAN Y,WANG L,et al. TP63 links chromatin
                   lineages[J]. Nat Commun. 2017,8(1):1379           remodeling and enhancer reprogramming to epidermal
             [48] YANG L,RODRIGUEZ B,MAYLE A,et al. DNMT3A           differentiation and squamous cell carcinoma development
                   loss drives enhancer hypomethylation in FLT3⁃ITD⁃asso⁃  [J]. Cell Mol Life Sci,2020,77(21):4325-4346
                   ciated leukemias[J]. Cancer Cell,2016,29(6):922-934  [61] LIU M,DU M,YU J,et al. CEBPA mutants down⁃regulate
             [49] XIONG L,WU F,WU Q,et al. Aberrant enhancer hypo⁃   AML cell susceptibility to NK⁃mediated lysis by disrup⁃
                   methylation contributes to hepatic carcinogenesis through  tion of the expression of NKG2D ligands,which can be
                   global transcriptional reprogramming[J]. Nat Commun,  restored by LSD1 inhibition[J]. Oncoimmunology,2022,
                   2019,10(1):335                                    11(1):2016158
             [50] REYES A A,MARCUM R D,HE Y. Structure and func⁃  [62] RAHNAMOUN H,HONG J,SUN Z,et al. Mutant p53
                   tion of chromatin remodelers[J]. J Mol Biol,2021,433  regulates enhancer ⁃ associated H3K4 monomethylation
                  (14):166929                                        through interactions with the methyltransferase MLL4
             [51] ARNAUD O,LE LOARER F,TIRODE F. BAFfling pa⁃        [J]. J Biol Chem,2018,293(34):13234-13246
                   thologies:alterations of BAF complexes in cancer[J].  [63] RAHNAMOUN H,LEE J,SUN Z,et al. RNAs interact
                   Cancer Lett,2018,419:266-279                      with BRD4 to promote enhanced chromatin engagement
             [52] ALVER B H,KIM K H,LU P,et al. The SWI/SNF chro⁃    and transcription activation[J]. Nat Struct Mol Biol,
                   matin remodelling complex is required for maintenance of  2018,25(8):687-697
                   lineage specific enhancers[J]. Nat Commun,2017,8:  [64] RAHNAMOUN H,LU H,DUTTKE S H,et al. Mutant
                   14648                                             p53 shapes the enhancer landscape of cancer cells in re⁃
             [53] NAKAYAMA R T,PULICE J L,VALENCIA A M,et al.        sponse to chronic immune signaling[J]. Nat Commun,
                   SMARCB1 is required for widespread BAF complex⁃me⁃  2017,8(1):754
                   diated activation of enhancers and bivalent promoters[J].  [65] JOZWIK K M,CHERNUKHIN I,SERANDOUR A A,et
                   Nat Genet,2017,49(11):1613-1623                   al. FOXA1 directs H3K4 monomethylation at enhancers
             [54] NAGARAJAN S,RAO S V,SUTTON J,et al. ARID1A in⁃     via recruitment of the methyltransferase MLL3[J]. Cell
                   fluences HDAC1/BRD4 activity,intrinsic proliferative ca⁃  Rep,2016,17(10):2715-2723
                   pacity and breast cancer treatment response[J]. Nat Gen⁃  [66] SUN Y,ZHOU B,MAO F,et al. HOXA9 reprograms the
                   et,2020,52(2):187-197                             enhancer landscape to promote leukemogenesis[J]. Can⁃
             [55] ST PIERRE R,COLLINGS C K,SAMÉ GUERRA D D,et        cer Cell,2018,34(4):643-658
                   al. SMARCE1 deficiency generates a targetable mSWI/  [67] GRYDER B E,YOHE M E,CHOU H C,et al. PAX3 ⁃
                   SNF dependency in clear cell meningioma[J]. Nat Genet,  FOXO1 establishes myogenic super enhancers and con⁃
                   2022,54(6):861-873                                fers BET bromodomain vulnerability[J]. Cancer Discov,
             [56] LAUBSCHER D,GRYDER B E,SUNKEL B D,et al.           2017,7(8):884-899
                   BAF complexes drive proliferation and block myogenic  [68] SKENE P J,HENIKOFF S. An efficient targeted nuclease
                   differentiation in fusion⁃positive rhabdomyosarcoma[J].  strategy for high⁃resolution mapping of DNA binding sites
                   Nat Commun,2021,12(1):6924                       [J]. Elife,2017,6:e21856
             [57] AUGELLO M A,LIU D,DEONARINE L D,et al. CHD1   [69] HO S W T,SHENG T,XING M,et al. Regulatory enhan⁃
                   loss alters AR binding at lineage⁃specific enhancers and  cer profiling of mesenchymal⁃type gastric cancer reveals
                   modulates distinct transcriptional programs to drive pro⁃  subtype ⁃ specific epigenomic landscapes and targetable
                   state tumorigenesis[J]. Cancer Cell,2019,35(4):603-  vulnerabilities[J]. Gut,2023,72(2):226-241
                   617                                          [70] ARNOLD C D,GERLACH D,STELZER C,et al. Genome⁃
             [58] MENON T,YATES J A,BOCHAR D A. Regulation of an⁃    wide quantitative enhancer activity maps identified by
                   drogen⁃responsive transcription by the chromatin remodel⁃  STARR⁃seq[J]. Science,2013,339(6123):1074-1077
                   ing factor CHD8[J]. Mol Endocrinol,2010,24(6):1165-  [71] WANG Y,LI J,LI J,et al. An enhancer⁃based analysis
                   1174                                              revealed a new function of androgen receptor in tumor
             [59] MARQUES J G,GRYDER B E,PAVLOVIC B,et al.                                    (下转第1478页)
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