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要通过未来进一步的大样本、多中心研究验证。②本 nosis of mechanical thrombectomy for acute stroke by ma⁃
研究中梗死核心体积的测量仅运用病变侧大脑半 chine learning combined with radiomics features[J]. Jour⁃
球 CBF 小于健侧大脑半球相同区域 30%的体积这 nal of Nanjing Medical University(Natural Sciences),
单一阈值,并未使用其他CBF阈值或使用脑血流量 2022,42(8):1165-1170
[4] NOGUEIRA R G,JADHAV A P,HAUSSEN D C,et al.
的阈值标准进行梗死核心体积测量的比较。
Thrombectomy 6 to 24 hours after stroke with a mismatch
综上所述,本研究发现部分 NCCT⁃CTP 不匹配
between deficit and infarct[J]. N Engl J Med,2018,378:
患者可从EVT中获益。影像评估前接受IVT以及更
11-21
高的基线NIHSS评分是出现NCCT⁃CTP不匹配的独 [5] ALBERS G W,MARKS M P,KEMP S,et al. Thrombecto⁃
立影响因素。本研究认为应该考虑发生NCCT⁃CTP my for stroke at 6 to 16 hours with selection by perfusion
不匹配的影响因素,在临床决策过程中,充分结合 imaging[J]. N Engl J Med,2018,378:708-718
临床因素,为此类患者实施合理的临床决策。 [6] KONG W Y,TAN B Y Q,NGIAM N J H et al. Validation
利益冲突声明: of serial alberta stroke program early CT score as an out⁃
所有作者声明不存在利益冲突。 come predictor in thrombolyzed stroke patients[J]. J
Conflict of Interests: Stroke Cerebrovasc Dis,2017,36:2264-2271
[7] SUI Y,CHEN W,CHEN C,et al. CTP⁃defined large core
The authors declare no conflict of interests.
作者贡献声明: is a better predictor of poor outcome for endovascular
张强负责数据收集、数据整理、撰写初稿、校对和编辑; treatment than ASPECTS⁃defined large core[J]. Stroke,
褚玥负责数据收集、数据整理、审阅和编辑论文;马高负责数 2024,55:1227-1234
据收集、数据整理、审阅和编辑论文;沈咣辰负责数据收集、 [8] 李晓慧,陈旭锋,汪 璇,等. 核心梗死体积对大血管闭
数据分析、数据可视化;施海彬审阅和编辑论文;吴飞云负责 塞性急性缺血性脑卒中早期临床预后的预测价值[J].
方法设计、审阅和编辑论文。 南京医科大学学报(自然科学版),2022,42(12):1716-
Author’s Contributions: 1721
LI X H,CHEN X F,WANG X,et al. The predictive value
ZHANG Qiang was responsible for data collection,organi⁃
of core infarction volume for the early clinical prognosis
zation,and manuscript writing;CHU Yue and MA Gao were re⁃
of large vessel occlusive acute ischemic stroke[J]. Jour⁃
sponsible for data collection,reviewing and editing the manu⁃
script;SHEN Guangchen was responsible for data collection, nal of Nanjing Medical University(Natural Sciences),
2022,42(12):1716-1721
analysis,and visualization;SHI Haibin participated in manu⁃
[9] HUO X,MA G,TONG X et al. Trial of endovascular ther⁃
script writing;WU Feiyun was responsible for experimental de⁃
apy for acute ischemic stroke with large infarct[J]. N
sign,fund support,and manuscript revision.
Engl J Med,2023,388:1272-1283
[参考文献]
[10]HAUSSEN D C,DEHKHARGHANI S,RANGARAJU S,
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学分会卒中学组,中国卒中学会急救医学分会. 急性缺 non⁃contrast CT ASPECTS(Alberta stroke program early
血性脑卒中急诊急救中国专家共识2018[J]. 中国卒中 CT score):correlation and clinical outcome prediction in
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Emergency Medicine Branch of the Chinese Geriatrics So⁃ [11]XING P,ZHOU X,SHEN F et al. Imaging mismatch be⁃
ciety,Stroke Group of the Emergency Medicine Branch of tween alberta stroke program early CT score and perfu⁃
the Chinese Medical Association,Emergency Medicine sion imaging may be a good variable for endovascular
Branch of the Chinese Stroke Society. Chinese expert con⁃ treatment[J]. Eur Radiol,2023,33:2629-2637
sensus on emergency treatment of acute ischemic stroke [12]ZAIDAT O O,YOO A J,KHATRI P,et al. Recommenda⁃
[J]. Chinese Journal of Stroke,2018,13(9):956-967 tions on angiographic revascularization grading standards
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报(自然科学版),2022,42(8):1165-1170 [14]LIN K,RAPALINO O,LAW M,et al. Accuracy of the al⁃
CHEN H Q,ZHANG H,GE X M,et al. Prediction of prog⁃ berta stroke program early CT score during the first 3

