Page 102 - 第10期
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第41卷第10期
               ·1520 ·                           南 京    医 科 大 学 学         报                        2021年10月


              容量最基本的参数,CSA⁃GA>340 mm 为发生反流                           ing of adverse events during procedural sedation:a con⁃
                                                2
              误吸的危险胃      [11] 。本研究中THRIVE组患者吸氧前                     sensus document from the World SIVA International Seda⁃
              后 CSA⁃GA 变化差异无统计学意义,可能与食管下                             tion Task Force[J]. Br J Anaesth,2012,108(1):13-20
                                                                [5] BOUVET L,MAZOIT J X,CHASSARD D,et al. Clinical
              端括约肌有关。食管下端括约肌是食管下端和胃
                                                                     assessment of the ultrasonographic measurement of antral
              连接处一高压区域,是防止胃内容物逆流入食管的
                                                                     area for estimating preoperative gastric content,andvol⁃
              屏障。食管下端括约肌压力正常值13~30 mmHg,本
                                                                     ume[J]. Anesthesiology,2011,114(5):1086-1092
              研究中 THRIVE 产生的动态气道正压为 2.7~7.4                     [6] MAJHOLM B,BARTHOLDY J,CLAUSEN H V,et al.
                    [12]
              cmH2O ,因此不会产生胃胀气。THRIVE提供高流                            Comparison between local anaesthesia with remifentanil
              量高浓度氧气,同时加温加湿,患者经鼻塞吸氧舒                                 and total intravenous anaesthesia for operative hystero⁃
              适度、耐受度较高,鼻咽部不适症状轻且发生率低,                                scopic procedures in day surgery[J]. Br J Anaesth,2012,
              且患者未出现气道损伤和气压伤,说明THRIVE在非                              108(2):245-253
              插管静脉麻醉下宫腔镜手术患者中的应用具有较高                            [7] HERMEZ L A,SPENCE C J,PAYTON M J,et al. A phys⁃
                                                                     iological study to determine the mechanism of carbon di⁃
              的安全性。
                                                                     oxide clearance during apnoea when using transnasal hu⁃
                  综上所述,快充式经鼻湿化高流量通气可改善
                                                                     midified rapid insufflation ventilatory exchange(THRIVE)
              非插管静脉麻醉下宫腔镜手术患者的氧合,减少术
                                                                    [J]. Anaesthesia,2019,74(4):441-449
              中体动,从而提高患者安全性,方便麻醉医生术中                            [8] PARKE R,MCGUINNESS S,ECCLESTON M. Nasal high
              管理,且THRIVE不增加反流误吸的风险,值得临床                              ⁃flow therapy delivers low level positive airway pressure
              推广。                                                   [J]. Br J Anaesth,2009,103(6):886-890
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                                                                     nasal oxygen availability for sedation decreases the use of
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                   event reporting tool to standardize the reporting and track⁃           [收稿日期] 2020-11-06
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