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容量最基本的参数,CSA⁃GA>340 mm 为发生反流 ing of adverse events during procedural sedation:a con⁃
2
误吸的危险胃 [11] 。本研究中THRIVE组患者吸氧前 sensus document from the World SIVA International Seda⁃
后 CSA⁃GA 变化差异无统计学意义,可能与食管下 tion Task Force[J]. Br J Anaesth,2012,108(1):13-20
[5] BOUVET L,MAZOIT J X,CHASSARD D,et al. Clinical
端括约肌有关。食管下端括约肌是食管下端和胃
assessment of the ultrasonographic measurement of antral
连接处一高压区域,是防止胃内容物逆流入食管的
area for estimating preoperative gastric content,andvol⁃
屏障。食管下端括约肌压力正常值13~30 mmHg,本
ume[J]. Anesthesiology,2011,114(5):1086-1092
研究中 THRIVE 产生的动态气道正压为 2.7~7.4 [6] MAJHOLM B,BARTHOLDY J,CLAUSEN H V,et al.
[12]
cmH2O ,因此不会产生胃胀气。THRIVE提供高流 Comparison between local anaesthesia with remifentanil
量高浓度氧气,同时加温加湿,患者经鼻塞吸氧舒 and total intravenous anaesthesia for operative hystero⁃
适度、耐受度较高,鼻咽部不适症状轻且发生率低, scopic procedures in day surgery[J]. Br J Anaesth,2012,
且患者未出现气道损伤和气压伤,说明THRIVE在非 108(2):245-253
插管静脉麻醉下宫腔镜手术患者中的应用具有较高 [7] HERMEZ L A,SPENCE C J,PAYTON M J,et al. A phys⁃
iological study to determine the mechanism of carbon di⁃
的安全性。
oxide clearance during apnoea when using transnasal hu⁃
综上所述,快充式经鼻湿化高流量通气可改善
midified rapid insufflation ventilatory exchange(THRIVE)
非插管静脉麻醉下宫腔镜手术患者的氧合,减少术
[J]. Anaesthesia,2019,74(4):441-449
中体动,从而提高患者安全性,方便麻醉医生术中 [8] PARKE R,MCGUINNESS S,ECCLESTON M. Nasal high
管理,且THRIVE不增加反流误吸的风险,值得临床 ⁃flow therapy delivers low level positive airway pressure
推广。 [J]. Br J Anaesth,2009,103(6):886-890
[9] ROMAN S,NIKOLA S N,KLIFFORD A,et al. High⁃flow
[参考文献]
nasal oxygen availability for sedation decreases the use of
[1] 顾小燕,花向东,许 锋,等. 200例不同程度宫腔粘连 general anesthesia during endoscopic retrograde cholangi⁃
的诊治[J]. 南京医科大学学报(自然科学版),2014,34 opancreatography and endoscopic ultrasound[J]. World J
(10):1429-1432 Gastroenterol,2016,22(47):10398-10405
[2] GEORGE S,HUMPHREYS S,WILLIAMS T,et al. Trans⁃ [10] PARKE R L,ECCLESTON M,MCGUINNESS S. The ef⁃
nasal humidified rapid insufflation ventilatory exchange in fects of flow on airway pressure during nasal high⁃flow
children requiring emergent intubation(Kids THRIVE):a oxygen therapy[J]. Respir Care,2011,56(8):1151-
protocol for a randomised controlled trial[J]. Bmj Open, 1155
2019,9(2):e025997 [11] CUBILLOS J,TSE C,CHAN V,et al. Bedside ultrasound
[3] YU J,XIANG B,SONG Y,et al. ED50 of propofol in com⁃ assessment of gastric content:an observational study[J].
bination with low ⁃ dose sufentanil for intravenous anaes⁃ Can J Anaesth,2012,59(4):416-423
thesia in hysteroscopy[J]. Basic Clin Pharmacol Toxicol, [12] HYUN J K,TAKASHI A. High⁃flow nasal oxygenation for
2019,125(5):460-465 anesthetic management[J]. Korean J Anesthesiol,2019,
[4] MASON K P,GREEN S M,PIACEVOLI Q,et al. Adverse 72(6):527-547
event reporting tool to standardize the reporting and track⁃ [收稿日期] 2020-11-06