Page 82 - 南京医科大学自然版
P. 82

第46卷第7期
               ·1028 ·                           南 京    医 科 大 学 学         报                        2026年7月


                   nasal recombinant hemagglutinin influenza vaccine on  [14]ONTIVEROS⁃PADILLA L,BACHELDER E M,AINSLIE
                   immune cells in mice[J]. Int J Antimicrob Agents,2025,  K M. Microparticle and nanoparticle ⁃ based influenza

                   66(6):107617                                      vaccines[J]. J Control Release,2024,376:880-898
             [4] LIANG Z H,ZHU H R,WANG X,et al. Adjuvants for  [15]XU Y C,YAN X Y,WEI T,et al. Transmucosal delivery
                   coronavirus vaccines[J]. Front Immunol,2020,11:589833  of nasal nanovaccines enhancing mucosal and systemic
             [5] SWIERCZEWSKA M,HAN H S,KIM K,et al. Poly⁃           immunity[J]. Nano Lett,2023,23(22):10522-10531
                   saccharide⁃based nanoparticles for theranostic nanomedi⁃  [16] MALTSEVA M,GALIPEAU Y,MCCLUSKIE P,et al.
                   cine[J]. Adv Drug Deliv Rev,2016,99:70-84         Systemic and mucosal antibody responses to SARS⁃CoV⁃
             [6] GOMEZ M,MCCOLLUM J,WANG H,et al. Development        2 variant⁃specific prime⁃and⁃boost and prime⁃and⁃spike
                   of a formulation platform for a spray⁃dried ,inhalable  vaccination:a comparison of intramuscular and intranasal
                   tuberculosis vaccine candidate[J]. Int J Pharm,2021,  bivalent vaccine administration in a murine model[J].

                   593:120121                                        Vaccines,2025,13(4):351
             [7] KASTURI S P,RASHEED M A U,HAVENAR⁃DAUGH⁃       [17]MA B J,TAO M X,LI Z L,et al. Mucosal vaccines for
                   TON C,et al. 3M⁃052,a synthetic TLR⁃7/8 agonist,induces  viral diseases:status and prospects[J]. Virology,2024,
                   durable HIV⁃1 envelope⁃specific plasma cells and humoral  593:110026
                   immunity in nonhuman primates[J]. Sci Immunol,2020,  [18] HERNANDEZ⁃FRANCO J F,YADAGIRI G,PATIL V,
                   5(48):eabb1025                                    et al. Intradermal vaccination against influenza with a
             [8] ABHYANKAR M M,MANN B J,STUREK J M,et al.            STING⁃targetednanoparticlecombinationadjuvantinduces
                   Development of COVID⁃19 vaccine using a dual Toll⁃like  superior cross⁃protective humoral immunity in swine com⁃
                   receptor ligand liposome adjuvant[J]. NPJ Vaccines,  pared with intranasal and intramuscular immunization[J].
                   2021,6:137                                        Vaccines,2023,11(11):1699
             [9] VOIGT E,ALSHARAYDEH A,KASAL D N,et al. ID93+   [19] CHEN R T,NIE M F,JIANG Y T,et al. A respiratory
                   GLA ⁃ 3M ⁃ 052 ⁃ LS vaccine candidate administered by  mucosal vaccine based on chitosan/aluminum adjuvant
                   heterologous routes improves BCG efficacy against TB[J].  induces both mucosal and systemic immune responses[J].
                   Front Immunol,2026,17:1797767                     Int J Pharm,2025,670:125168
             [10]MOKALLA V R,GUNDARAPU S,KAUSHIK R S,et al.     [20] SONG Y F,MEHL F,ZEICHNER S L.Vaccine strategies
                   Influenza vaccines:current status,adjuvant strategies,  to elicit mucosal immunity[J]. Vaccines,2024,12(2):
                   and efficacy[J]. Vaccines,2025,13(9):962          191
             [11]VERMA A,BENIWAL N,PUTTA C L,et al. CpG ODNs:   [21] NELSON S A,SANT A J. Potentiating lung mucosal
                   precision immunotherapy and recent trends in nano ⁃  immunity through intranasal vaccination[J]. Front Immu⁃
                   enabled nucleotide delivery[J]. Crit Rev Ther Drug Carr  nol,2021,12:808527
                   Syst,2026,43(1):57-95                        [22]YIN J H,ZHAO Y Z,HUANG F,et al. Immune response
             [12]LIANG Z H,BAO H,YAO Z Y,et al. The orientation of   and homeostasis mechanism following administration of
                   CpG conjugation on aluminum oxyhydroxide nanoparticles  BBIBP⁃CorV SARS⁃CoV⁃2 inactivated vaccine[J]. Inno⁃
                   determines the immunostimulatory effects of combination  vation,2023,4(1):100359
                   adjuvants[J]. Biomaterials,2024,308:122569   [23] ZHANG Z H,HONG W Q,ZHANG Y,et al. Mucosal
             [13]BEHZAD H,HUCKRIEDE A L W,HAYNES L,et al.            immunity and vaccination strategies:current insights and
                   GLA⁃SE,a synthetic toll⁃like receptor 4 agonist,enhances  future perspectives[J]. Mol Biomed,2025,6(1):57
                   T⁃cell responses to influenza vaccine in older adults[J].  (收稿:2026-01-26;修回:2026-05-22;录用:2026-05-27)
                   J Infect Dis,2012,205(3):466-473                                           (本文编辑:蒋       莉)
   77   78   79   80   81   82   83   84   85   86   87